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Documentos Principais

B3770

Sigma-Aldrich

(+)-Biotinamidohexanoic acid hydrazide

≥90% (TLC), powder

Sinônimo(s):

(+)-Biotin-ε-aminocaproyl hydrazide, (+)-Biotin-X-hydrazide, (+)-Biotinamidocaproyl hydrazide, BACH, N-(+)-Biotinyl-6-aminohexanoic hydrazide

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About This Item

Fórmula empírica (Notação de Hill):
C16H29N5O3S
Número CAS:
Peso molecular:
371.50
Número MDL:
Código UNSPSC:
12352125
eCl@ss:
34058011
ID de substância PubChem:
NACRES:
NC.07

Nível de qualidade

Ensaio

≥90% (TLC)

Formulário

powder

solubilidade

DMSO: 25 mg/mL

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

[H][C@]12CS[C@@H](CCCCC(=O)NCCCCCC(=O)NN)[C@@]1([H])NC(=O)N2

InChI

1S/C16H29N5O3S/c17-21-14(23)8-2-1-5-9-18-13(22)7-4-3-6-12-15-11(10-25-12)19-16(24)20-15/h11-12,15H,1-10,17H2,(H,18,22)(H,21,23)(H2,19,20,24)/t11-,12-,15-/m0/s1

chave InChI

IJJWOSAXNHWBPR-HUBLWGQQSA-N

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Aplicação

Biotinylation reagent with aminocaproic spacer for aldehyde groups (e.g., periodate-oxidized sugars) and carboxylic acids. Typically used for coupling to glycoproteins through the carbohydrate by hydrazone bond formation.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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M B Rosenberg et al.
Journal of neurochemistry, 46(2), 641-648 (1986-02-01)
beta-nerve growth factor (NGF) was modified by biotinylation via carboxyl group substitution (C-bio-NGF) using biotin hydrazide and the coupling reagent 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide, under reaction conditions that yielded an average of 3 biotin additions per NGF subunit. NGF was also biotinylated through
S Spiegel et al.
Journal of immunology (Baltimore, Md. : 1950), 127(2), 572-575 (1981-08-01)
Biotin hydrazide was attached covalently to the aldehyde groups produced by periodate oxidation of bovine brain gangliosides. These modified gangliosides were incorporated into mature rat thymocytes by incubation of the biotinyl gangliosides in the culture medium containing these cells. Avidin
A new biotinylating system for DNA using biotin aminocaproyl hydrazide and glutaraldehyde.
T Takahashi et al.
Nucleic acids research, 17(12), 4899-4900 (1989-06-26)
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