D80002

DCC

99%

• Sinônimo(s): N,N′-Dicyclohexylcarbodiimide
• Fórmula linear: C₆H₁₁N=C=NC₆H₁₁
• Número CAS: 538-75-0
• Peso molecular: 206.33
• Beilstein: 610662
• Número CE: 208-704-1
• Número MDL: MFCD00011659
• Código UNSPSC: 12352111
• ID de substância PubChem: 24894174
• NACRES: NA.22

Propriedades

• Nível de qualidade: 200
• Ensaio: 99%
• Formulário: solid
• adequação da reação: reaction type: Coupling Reactions
• p.e.: 122-124 °C/6 mmHg (lit.)
• pf: 34-35 °C (lit.)
• cadeia de caracteres SMILES: C1CCC(CC1)N=C=NC2CCCCC2
• InChI: 1S/C13H22N2/c1-3-7-12(8-4-1)14-11-15-13-9-5-2-6-10-13/h12-13H,1-10H2
• chave InChI: QOSSAOTZNIDXMA-UHFFFAOYSA-N
• Informações sobre genes: human ... EPHX2(2053) ; mouse ... Ephx2(13850)

Descrição

Descrição geral

DCC is the acronym for N,N′-dicyclohexylcarbodiimide. In peptide synthesis, it is utilized for the activation of carboxyl group. The structure of DCC has been analyzed based on IR and Raman spectral data. It mediates the esterification of poly(vinyl alcohol) with free levulinic acid to form poly(vinyl alcohol-co-vinyl levulinate).

Aplicação

Carboxy group activating reagent for peptide synthesis.

DCC has been used in the preparation of titanate nanotubes-phthalocyanine(TiONts-Pc) nanohybrids and 7-((tert-butyldimethylsilyl)oxy)hepta-2,4-diyn-1-yl propynoate.

DCC may be used to promote the esterification of
7-((tert-butyldimethylsilyl)oxy)hepta-2,4-diyn-1-ol with propiolic acid to form 7-((tert-butyldimethylsilyl)oxy)hepta-2,4-diyn-1-yl propynoate.
It can also used to synthesize:

• 1,3-Thiazetedine derivatives via [2+2] cycloaddition with 2-phenylethenyl- and 2-(4-nitrophenyl)ethenyl isothiocyanates.
• 1,3,5-Oxadiazine-4-thiones via [4+2] cycloaddition with benzoyl isothiocyanates.
• Sterically hindered 1,3,4-oxadiazole derivatives by reacting with (N-isocyanimino)triphenylphosphorane in the presence of aromatic (or heteroaromatic) carboxylic acids.

Informações de segurança

• Pictogramas: GHS06,GHS05
• Palavra indicadora: Danger
• Frases de perigo: H302,H311,H317,H318
• Declarações de precaução: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1
• Código de classe de armazenamento: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 235.4 °F - closed cup
• Ponto de fulgor (°C): 113 °C - closed cup
• Equipamento de proteção individual: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges