A7793
Ácido 5-aminolevulínico
BioReagent, suitable for cell culture, powder, ≥98%
Sinônimo(s):
δÁcido 5-aminolevulínico, ALA, Ácido 5-amino-4-oxopentanoico, Ácido 5-aminolevulínico
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About This Item
Fórmula linear:
NH2CH2C(O)CH2CH2COOH · HCl
Número CAS:
Peso molecular:
167.59
Beilstein:
3690651
Número CE:
Número MDL:
Código UNSPSC:
12352209
ID de substância PubChem:
NACRES:
NA.75
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linha de produto
BioReagent
Nível de qualidade
Ensaio
≥98%
Formulário
powder
técnica(s)
cell culture | mammalian: suitable
solubilidade
H2O: 50 mg/mL
temperatura de armazenamento
−20°C
cadeia de caracteres SMILES
Cl[H].NCC(=O)CCC(O)=O
InChI
1S/C5H9NO3.ClH/c6-3-4(7)1-2-5(8)9;/h1-3,6H2,(H,8,9);1H
chave InChI
ZLHFONARZHCSET-UHFFFAOYSA-N
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Aplicação
5-Aminolevulinic acid formed from glycine and succinyl CoA by ALA synthase is the first compound in prophyrin biosynthesis pathway. 5-Aminolevulinic acid is used in photodynamic therapy. This compound may be used to study the effects of photodynamic therapy in vitro.
Ações bioquímicas/fisiológicas
Intermediário na biossíntese de heme.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Outcome in osteochondral allografting is limited by the immunological incompatibility of the grafted tissue. Based on a resistance of chondrocytes to photodynamic therapy in cell culture it is proposed that 5-aminolevulinic acid-based photodynamic therapy (5-ALA-PDT) might be used to inactivate
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Previous studies in high-grade gliomas (HGGs) have indicated that protoporphyrin IX (PpIX) accumulates in higher concentrations in tumor tissue, and, when used to guide surgery, it has enabled improved resection leading to increased progression-free survival. Despite the benefits of complete
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In glioma surgery, Protoporphyrin IX (PpIX) fluorescence may identify residual tumor that could be resected while minimizing damage to normal brain. We demonstrate that improved sensitivity for wide-field spectroscopic fluorescence imaging is achieved with minimal disruption to the neurosurgical workflow
J P Golding et al.
Veterinary and comparative oncology, 15(4), 1543-1552 (2017-01-28)
Photodynamic therapy (PDT) holds great promise in treating veterinary and human dermatological neoplasms, including equine sarcoids, but is currently hindered by the amount of photosensitiser and light that can be delivered to lesions thicker than around 2 mm, and by the
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