85578

Spermidine trihydrochloride

BioXtra, ≥99.5% (AT)

• Sinônimo(s): N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride
• Fórmula linear: NH₂(CH₂)₃NH(CH₂)₄NH₂ · 3HCl
• Número CAS: 334-50-9
• Peso molecular: 254.63
• Beilstein: 3552356
• Número CE: 206-379-0
• Número MDL: MFCD00012918
• Código UNSPSC: 12352116
• ID de substância PubChem: 57653005
• NACRES: NA.26

Propriedades

• linha de produto: BioXtra
• Nível de qualidade: 100
• Ensaio: ≥99.0% (TLC); ≥99.5% (AT)
• Formulário: powder
• Impurezas: insoluble matter, passes filter test
• pH: 3.0-6.0 (25 °C, 1 M in H₂O)
• pf: 257-259 °C (lit.)
• solubilidade: H₂O: 1 M at 20 °C, clear, colorless
• traços de ânion: sulfate (SO₄^2-): ≤50 mg/kg
• traços de cátion: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤10 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 1 M in H₂O
• Absorção UV: λ: 260 nm A_max: 0.2; λ: 280 nm A_max: 0.1
• cadeia de caracteres SMILES: Cl[H].Cl[H].Cl[H].NCCCCNCCCN
• InChI: 1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H
• chave InChI: LCNBIHVSOPXFMR-UHFFFAOYSA-N

Descrição

Descrição geral

Spermidine trihydrochloride is an aliphatic polyamine. Its crystalline structure has been studied. It has been reported to preserve the nuclei and prevent proteolytic degradation of histones during the macronuclei isolation from Tetrahymena pyriformis.

Aplicação

Spermidine trihydrochloride is used for the following applications:

• DNA extraction and restriction endonuclease digestion
• Nuclear transplantation
• During the chemical analyses of the squid species Todaropsis eblanae
• As one of the agents in intercalating drug.
• Platelet aggregation

It may be used in the synthesis of palladium complexes like [sperH₃]₂[PdCl₄]₃, [PdCl₂(sperH)]₂[PdCl₄], and [(PdCl₂)₃(sper)₂] by reacting with K₂PdCl₄ and PdCl₂.

Ações bioquímicas/fisiológicas

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T₄ polynucleotide kinase activity.

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T₄ polynucleotide kinase activity.

Atenção

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

Outras notas

Buffer component for chromosome isolation in bivariate flow cytogenetic analysis and sorting.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H315,H319
• Declarações de precaução: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Classificações de perigo: Eye Irrit. 2 - Skin Irrit. 2
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves