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Merck
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Key Documents

83697

Sigma-Aldrich

Rhodamine 6G

suitable for fluorescence, BioReagent

Sinônimo(s):

Basic Red 1

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About This Item

Fórmula linear:
C28H31N2O3Cl
Número CAS:
Peso molecular:
479.01
Número do índice de cores:
45160
Beilstein:
3900071
Número CE:
Número MDL:
Código UNSPSC:
12171500
ID de substância PubChem:
NACRES:
NA.32

linha de produto

BioReagent

Nível de qualidade

forma

powder

solubilidade

H2O: soluble
ethanol: soluble

fluorescência

λex 528 nm; λem 551 nm in methanol

adequação

suitable for fluorescence

cadeia de caracteres SMILES

Cl.CCNc1cc2OC3=CC(=N/CC)\C(C)=CC3=C(c2cc1C)c4ccccc4C(=O)OCC

InChI

1S/C28H30N2O3.ClH/c1-6-29-23-15-25-21(13-17(23)4)27(19-11-9-10-12-20(19)28(31)32-8-3)22-14-18(5)24(30-7-2)16-26(22)33-25;/h9-16,29H,6-8H2,1-5H3;1H/b30-24+;

chave InChI

VYXSBFYARXAAKO-WTKGSRSZSA-N

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Aplicação

Rhodamine 6G has been used as a leukocyte marker to study the interaction between leukocytes and the vascular endothelium. It has also been used to label platelets.

Ações bioquímicas/fisiológicas

Rhodamine 6G is a rhodamine analog useful in P-glycoprotein (Pgp) efflux assays. It has been used to characterize kinetics of multidrug resistance protein 1 (MRP1)-mediated efflux.
A rhodamine analog useful in Pgp efflux assays. Has been used to characterize kinetics of MRP1- mediated efflux.

Nota de análise

λmax. ∼530 nm, E(1%/1cm) ∼2000-2300 (96% Ethanol)

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Sens. 1

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


Certificados de análise (COA)

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Journal of thrombosis and haemostasis : JTH, 12(12), 2120-2130 (2014-09-30)
Essential thrombocythemia (ET) and polycythemia vera (PV) are myeloproliferative neoplasms (MPNs) that share the JAK2(V617F) mutation in hematopoietic stem cells, leading to excessive production of predominantly platelets in ET, and predominantly red blood cells (RBCs) in PV. The major cause
MinKwan Kim et al.
Scientific reports, 5, 16525-16525 (2015-11-18)
Superresolution fluorescence microscopy possesses an important role for the study of processes in biological cells with subdiffraction resolution. Recently, superresolution methods employing the emission properties of fluorophores have rapidly evolved due to their technical simplicity and direct applicability to existing
Bo Hu et al.
Biosensors & bioelectronics, 49, 499-505 (2013-07-03)
The detection of mercury in biological systems and its imaging is of highly importance. In this work, a ratiometric fluorescence sensor is developed based on fluorescence resonance energy transfer (FRET) with N-acetyl-L-cysteine functionalized quantum dots (NAC-QDs) as donor and Rhodamine
Brendan L Darby et al.
Journal of the American Chemical Society, 136(31), 10965-10973 (2014-07-22)
This study highlights a crucial but often overlooked consideration during sample preparation involving surface-adsorbing species: the competition between analyte adsorption and analyte diffusion/mixing strongly affects the distribution of analytes throughout the sample. In cases of fast analyte adsorption, we argue
Asmahan Abu-Arish et al.
Biophysical journal, 97(8), 2164-2178 (2009-10-22)
The GTPase Ran is a key regulator of molecular transport through nuclear pore complex (NPC) channels. To analyze the role of Ran in its nuclear transport function, we used several quantitative fluorescence techniques to follow the distribution and dynamics of

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