F6377

Fluorescein sodium salt

Powder

• Sinônimo(s): Acid Yellow 73, D&C;Yellow No. 8, NaFl, NaFluo, Sodium fluorescein, Uranine
• Fórmula empírica (Notação de Hill): C₂₀H₁₀Na₂O₅
• Número CAS: 518-47-8
• Peso molecular: 376.27
• Número do índice de cores: 45350
• Beilstein: 3833041
• Número CE: 208-253-0
• Número MDL: MFCD00167039
• Código UNSPSC: 12171500
• ID de substância PubChem: 24894907
• NACRES: NA.47

Propriedades

• product name: Fluorescein sodium salt, used as fluorescent tracer
• Nível de qualidade: 200
• forma: powder
• cor: orange to brown
• pH: 8.3 (20 °C, 10 g/L)
• pf: >300 °C
• solubilidade: H₂O: 1 mg/mL
• densidade: 0.78 g/cm³ at 29.6 °C (85.3 °F at 699.7 hPa)
• fluorescência: λ_ex 460 nm; λ_em 515 nm(lit.)
• aplicação(ões): diagnostic assay manufacturing; hematology; histology
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: [Na+].[Na+].[O-]c1ccc2c(Oc3cc([O-])ccc3C24OC(=O)c5ccccc45)c1
• InChI: 1S/C20H12O5.2Na/c21-11-5-7-15-17(9-11)24-18-10-12(22)6-8-16(18)20(15)14-4-2-1-3-13(14)19(23)25-20;;/h1-10,21-22H;;/q;2*+1/p-2
• chave InChI: RGPLGPBQJOQFJS-UHFFFAOYSA-L

Descrição

Descrição geral

Fluorescein is a xanthene dye and is a common labeling agent in biology.

Aplicação

Fluorescein sodium salt has been used as a solute to study microvessel permeability. It has been used as a test molecule to study blood barrier penetration.

Water soluble fluorescent dye used in permeability and vascular perfusion studies due to its small molecular radius. Sodium fluorescein is used as a fluorescent tracer to study blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) permeability in rodent models. The dye was used as a probe substrate in the study of organic anion transporting polypeptide (OATP) mediated drug transport in hepatocytes. Sodium fluorescein was also used to monitor in situ solute transportation into bone through fluorescence recovery after photobleaching (FRAP).

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 423.7 °F - Pensky-Martens closed cup
• Ponto de fulgor (°C): 217.6 °C - Pensky-Martens closed cup
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)