78830

Fluoreto de fenilmetanosulfonil

≥99.0% (T)

• Sinônimo(s): αFluoreto de α-toluenosulfonil, Fluoreto de benzilsulfonil, Fluoreto de fenilmetilsulfonil, PMSF
• Fórmula empírica (Notação de Hill): C₇H₇FO₂S
• Número CAS: 329-98-6
• Peso molecular: 174.19
• Beilstein: 2088311
• Número CE: 206-350-2
• Número MDL: MFCD00007424
• Código UNSPSC: 12352202
• ID de substância PubChem: 57652759
• NACRES: NA.77

Propriedades

• fonte biológica: synthetic
• Ensaio: ≥99.0% (T)
• Formulário: powder or crystals
• Impurezas: ≤0.1% water
• pf: 92-95 °C
• solubilidade: anhydrous isopropanol: soluble 35 mg/mL, clear to faintly hazy, colorless to faintly yellow (Heating required)
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: FS(=O)(=O)Cc1ccccc1
• InChI: 1S/C7H7FO2S/c8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2
• chave InChI: YBYRMVIVWMBXKQ-UHFFFAOYSA-N

Descrição

Aplicação

Phenylmethanesulfonyl fluoride has been used as a component in radioimmunoprecipitation buffer for western blot analysis. It has also been used as a component in the RAW264.7 cell lysis buffer for western blotting.

Ações bioquímicas/fisiológicas

Phenylmethanesulfonyl fluoride has the ability to enhance the stability of plasma lipidome in lipidomic and metabolomic analysis. This serine protease inhibitor reduces the naloxone-precipitated withdrawal jumping behavior in morphine-dependent mice.

Outras notas

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Specific trypsin and chymotrypsin inhibitor. Less toxic substitute for diisopropylfluorophosphate. Potentiates the effects of ischemia on brain mitochondria through its inhibition of phospholipase C.

Specific trypsin and chymotrypsin inhibitor; Less toxic substitute for diisopropylfluorophosphate. Potentiates the effects of ischemia on brain mitochondria through its inhibition of phospholipase C.

Informações de segurança

• Pictogramas: GHS06,GHS05
• Palavra indicadora: Danger
• Frases de perigo: H301,H314
• Declarações de precaução: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Classificações de perigo: Acute Tox. 3 Oral - Skin Corr. 1B
• Código de classe de armazenamento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges