44213
Thromboplastin from rabbit
Sinônimo(s):
Thromboplastin, Factor III, Thrombokinase
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About This Item
Produtos recomendados
fonte biológica
rabbit
Nível de qualidade
forma
lyophilized solid
nº de adesão UniProt
temperatura de armazenamento
2-8°C
Informações sobre genes
rabbit ... F3(100009127)
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Aplicação
Thromboplastin from rabbit has been used:
- as a standard in tissue factor procoagulant activity assay (TF-PCA)
- in pulmonary embolism assay
- as a positive control in clotting assay using human plasma
Ações bioquímicas/fisiológicas
Thromboplastin (Tissue factor) is a transmembrane protein, the chief in vivo activator of blood coagulation that leads to thrombin generation and fibrin deposition. It is also important in the activation of the coagulation protease cascade and is involved in the lethality of sepsis.,
Thromboplastin from rabbit might be used to produce disseminated intravascular coagulation (DIC) in animal models.
Embalagem
One vial contains 3-4 mg thromboplastin.
Reconstituição
Reconstitute the content of 1 vial in 4 ml 10 mm CaCl2
Palavra indicadora
Danger
Frases de perigo
Declarações de precaução
Classificações de perigo
Resp. Sens. 1
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 1
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
Certificados de análise (COA)
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M E Bromberg et al.
Proceedings of the National Academy of Sciences of the United States of America, 92(18), 8205-8209 (1995-08-29)
Several studies have established a link between blood coagulation and cancer, and more specifically between tissue factor (TF), a transmembrane protein involved in initiating blood coagulation, and tumor metastasis. In the study reported here, a murine model of human melanoma
J Erlich et al.
Infection and immunity, 67(5), 2540-2546 (1999-05-04)
Tissue factor (TF) is the major activator of the coagulation protease cascade and contributes to lethality in sepsis. Despite several studies analyzing TF expression in animal models of endotoxemia, there remains debate about the cell types that are induced to
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Macrophages resident in different organs express distinct genes, but understanding how this diversity fits into tissue-specific features is limited. Here, we show that selective expression of coagulation factor V (FV) by resident peritoneal macrophages in mice promotes bacterial clearance in
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