H3393
Heparin sodium salt from porcine intestinal mucosa
Grade I-A, ≥180 USP units/mg
Sinônimo(s):
Sodium heparin
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About This Item
Produtos recomendados
fonte biológica
Porcine intestinal mucosa
Nível de qualidade
tipo
Grade I-A
forma
powder
atividade específica
≥180 USP units/mg
cor
beige
faixa de pH útil
5.0 - 7.5
solubilidade
H2O: 50 mg/mL, clear, colorless to faintly yellow
aplicação(ões)
clinical research
diagnostic assay manufacturing
life science and biopharma
temperatura de armazenamento
room temp
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Categorias relacionadas
Descrição geral
Heparin is a glycosaminoglycan (GAG) belonging to the mucopolysaccharides family, known for its potent anticoagulant properties. This extensively sulfated polysaccharide consists of D-glucosamine and hexuronic acid linked via glycosidic linkages. It finds wide application in biochemical research and cell culture studies.
Aplicação
Heparin sodium salt from porcine intestinal mucosa has been supplemented in the medium prepared for insemination of oocytes with spermatozoa. Heparin sodium salt from porcine intestinal mucosa has been used:
- to check the effect of heparin on FGF21 (fibroblast growth factor 21) signaling.
- in immunostaining of mice brain sections
- to quantify white blood cells and red blood cells in Sparus aurata blood samples
- in anticoagulation and severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) inhibition assay
Ações bioquímicas/fisiológicas
Heparin is mainly responsible for the delay in the coagulation of blood. It enhances the antithrombin-mediated inactivation of proteases in the coagulation pathway.
Heparin is synthesized in mast cells and mediators such as histamine and is associated with allergy and inflammatory activity. Heparin shows therapeutic effects against venous thrombosis and pulmonary embolism, helps in preventing re-thrombosis post thrombolysis, and manages arterial thrombosis in patients who suffer from acute myocardial infarction. Heparin shows anti-inflammatory action in many inflammatory conditions such as burns, bronchial asthma, and ulcerative colitis.
Heparin is synthesized in mast cells and mediators such as histamine and is associated with allergy and inflammatory activity. Heparin shows therapeutic effects against venous thrombosis and pulmonary embolism, helps in preventing re-thrombosis post thrombolysis, and manages arterial thrombosis in patients who suffer from acute myocardial infarction. Heparin shows anti-inflammatory action in many inflammatory conditions such as burns, bronchial asthma, and ulcerative colitis.
Outras notas
For additional information on our range of Biochemicals, please complete this form.
Heparin solutions should not be autoclaved as additional crosslinking of the sugars may occur at high temperatures. It should not be frozen as well.
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Produtos recomendados
Heparin for diagnostic manufacturing is available as product number SRE0027
produto comparável
produto relacionado
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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L Peter Sarin et al.
Nucleic acids research, 37(4), 1182-1192 (2009-01-09)
The RNA-dependent RNA polymerase (RdRP) of double-stranded RNA (dsRNA) viruses performs both RNA replication and transcription. In order to initiate RNA polymerization, viral RdRPs must be able to interact with the incoming 3' terminus of the template and position it
Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models--association with liver and adipose tissue effects.
Xu J et al.
American Journal of Physiology. Endocrinology and Metabolism, 297, E1105-E1105 (2009)
Bovine immature oocytes acquire developmental competence during meiotic arrest in vitro.
Hashimoto S et al.
Biology of Reproduction, 66, 1696-1696 (2002)
Sheikh Fayaz Ahmad et al.
Molecular neurobiology, 54(6), 4390-4400 (2016-06-28)
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Efficient inhibition of cell-pathogen interaction to prevent subsequent infection is an urgent but yet unsolved problem. In this study, the synthesis and functionalization of novel multivalent 2D carbon nanosystems as well as their antiviral efficacy in vitro are shown. For
Artigos
Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.
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