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Documentos Principais

Y0001304

Butyl methanesulfonate

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

NSC 36060

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About This Item

Fórmula empírica (Notação de Hill):
C5H12O3S
Número CAS:
1912-32-9
Peso molecular:
152.21
Código UNSPSC:
41116107
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

imatinib

fabricante/nome comercial

EDQM

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

[S](=O)(=O)(OCCCC)C

InChI

1S/C5H12O3S/c1-3-4-5-8-9(2,6)7/h3-5H2,1-2H3

chave InChI

LFLBHTZRLVHUQC-UHFFFAOYSA-N

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Butyl methanesulfonate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number

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Sigma-Aldrich

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Sigma-Aldrich

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Methyl p-toluenesulfonate

Methyl p-toluenesulfonate 98%

Sigma-Aldrich

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Sodium iodide ACS reagent, ≥99.5%

Sigma-Aldrich

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Sigma-Aldrich

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Sodium thiosulfate

H Hoppe et al.
Mutation research, 250(1-2), 411-421 (1991-09-11)
Cells of the human lymphoblast line WI-L2 and its derivative TK-6 were synchronized by centrifugal elutriation and cell-cycle dependent mutation to 6TGR (HPRT) and OUAR (Na+, K+ ATPase) measured. Bromodeoxyuridine induced 6TGR and OUAR mutations within S phase while butylmethyl-sulfonate
R Saffhill
Carcinogenesis, 5(5), 621-625 (1984-05-01)
The reaction of N-n-butyl-N-nitrosourea ( BNU ) and n-butyl methanesulphonate (BMS) with DNA has been investigated. In addition to the expected n- butylpurines formed on reaction with BNU some rearranged sec-butyl-adducts were also observed, indicating that a carbonium ion is
J C Ball et al.
Environmental and molecular mutagenesis, 13(2), 100-106 (1989-01-01)
This report describes experiments in which a chiral alkyl methanesulfonate was used to investigate possible mechanisms by which alkylating agents cause their mutagenic, cytotoxic, and clastogenic effects. Optically active enantiomers and the racemic mixture of 2-butyl methanesulfonate (2-BMS) were cytotoxic
A R Rao
International journal of cancer, 28(1), 105-110 (1981-07-15)
The influence of pregnant mare serum gonadotropin (PSGM) on the induction of ovarian tumors by carcinogen(DMBA) and/or mutagens (EMS and BMS) has been studied in Swiss albino mice. Priming of the ovaries of 6-week-old mice with PMSG (50 IU/mouse) 24

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