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Documentos Principais

PHR1476

Supelco

Diethyl Phthalate

Pharmaceutical Secondary Standard; Certified Reference Material

Sinônimo(s):

Diethyl phthalate

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About This Item

Fórmula linear:
C6H4-1,2-(CO2C2H5)2
Número CAS:
Peso molecular:
222.24
Beilstein:
1912500
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

certified reference material
pharmaceutical secondary standard

Nível de qualidade

Agency

traceable to Ph. Eur. D1410000
traceable to USP 1193505

densidade de vapor

7.66 (vs air)

pressão de vapor

1 mmHg ( 100 °C)

família API

diethyl phthalate

Certificado de análise (CofA)

current certificate can be downloaded

temperatura de autoignição

854 °F

Lim. expl.

0.75 %, 187 °F

embalagem

pkg of 1 g

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

índice de refração

n20/D 1.502 (lit.)

p.e.

298-299 °C (lit.)

pf

−3 °C (lit.)

densidade

1.12 g/mL at 25 °C (lit.)

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-30°C

cadeia de caracteres SMILES

CCOC(=O)c1ccccc1C(=O)OCC

InChI

1S/C12H14O4/c1-3-15-11(13)9-7-5-6-8-10(9)12(14)16-4-2/h5-8H,3-4H2,1-2H3

chave InChI

FLKPEMZONWLCSK-UHFFFAOYSA-N

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Descrição geral

Diethyl Phthalate is a phthalic acid ester, commonly synthesized by the condensation of the carboxy groups of phthalic acid with methanol.. It is used as a solvent for fragrance in cosmetic formulations and personal care products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

Diethyl Phthalate may be used as a pharmaceutical reference standard for the determination of the analyte in cosmetic products, pharmaceutical formulations and dietary supplements by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAA3024 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

338.0 °F - closed cup

Ponto de fulgor (°C)

170 °C - closed cup


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Certificados de análise (COA)

Lot/Batch Number

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Identification of phthalates in medications and dietary supplement formulations in the United States and Canada
Kelley K, et al.
Environmental Health Perspectives, 120(3), 379-384 (2011)
Phthalic Acid and Derivatives
Ullmann's Encyclopedia of Industrial Chemistry (2007)
Gas chromatography in routine pharmaceutical analysis
Baines CB and Proctor KA
The Journal of Pharmacy and Pharmacology, 11(S1), 230T-234T (1959)
Analysis of consumer cosmetic products for phthalate esters.
Hubinger JC and Havery DC
Journal of Cosmetic Science, 57(2), 127-137 (2006)
Simultaneous determination of seven phthalates and four parabens in cosmetic products using HPLC-DAD and GC-MS methods
Shen Y-H, et al.
Journal of Separation Science, 30(1), 48-54 (2007)

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