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Documentos Principais

PHR1619

Supelco

Beclomethasone Dipropionate

Pharmaceutical Secondary Standard; Certified Reference Material

Sinônimo(s):

Beclomethasone dipropionate, 9-Chloro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate

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About This Item

Fórmula empírica (Notação de Hill):
C28H37ClO7
Número CAS:
Peso molecular:
521.04
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

certified reference material
pharmaceutical secondary standard

Nível de qualidade

Agency

traceable to BP 30
traceable to Ph. Eur. B0305000
traceable to USP 1048506

família API

beclometasone

Certificado de análise (CofA)

current certificate can be downloaded

embalagem

pkg of 1 g

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-30°C

cadeia de caracteres SMILES

CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]12C

InChI

1S/C28H37ClO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1

chave InChI

KUVIULQEHSCUHY-XYWKZLDCSA-N

Informações sobre genes

human ... NR3C1(2908)

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Descrição geral

Beclomethasone Dipropionate is a second generation anti-inflammatory corticosteroid used for the treatment of allergic rhinitis.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

Beclomethasone Dipropionate may be used as a pharmaceutical secondary reference standard for the determination of the analyte in biological fluids and ear drops formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAC2965 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictogramas

Health hazard

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Repr. 2 - STOT RE 2

Órgãos-alvo

Adrenal gland,Immune system,Bone

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number

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Determination of beclomethasone dipropionate, clotrimazole, chloramphenicol and lidocaine in pharmaceutical formulations using a novel RP-HPLC method
Reddy MU, et al.
International Journal of Pharma and Bio Sciences, 2(1), 453-462 (2011)
Efficacy and safety of oral beclomethasone dipropionate in ulcerative colitis: a systematic review and meta-analysis
Manguso F, et al.
Testing, 11(11), e0166455-e0166455 (2016)
Simultaneous determination of beclomethasone, beclomethasone monopropionate and beclomethasone dipropionate in biological fluids using a particle beam interface for combining liquid chromatography with negative-ion chemical ionization mass spectrometry
Girault J, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 564(1), 43-53 (1991)
Efficacy and safety of beclomethasone dipropionate nasal aerosol in children with perennial allergic rhinitis
Berger WE, et al.
Annals of Allergy, Asthma & Immunology, 115(2), 130-136 (2015)
Determination of beclomethasone dipropionate, clotrimazole, chloramphenicol and lidocaine in pharmaceutical formulations using a novel RP-HPLC method
Reddy MU, et al.
International Journal of Pharmacy and Biological Sciences, 2(1), 453-462 (2011)

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