B3022

Beclomethasone dipropionate

analytical standard, for drug analysis

• Sinônimo(s): 9-Chloro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate
• Fórmula empírica (Notação de Hill): C₂₈H₃₇ClO₇
• Número CAS: 5534-09-8
• Peso molecular: 521.04
• Número CE: 226-886-0
• Número MDL: MFCD00135613
• Código UNSPSC: 41116107
• ID de substância PubChem: 329773210
• NACRES: NA.24

Propriedades

• grau: analytical standard, for drug analysis
• Nível de qualidade: 200
• Ensaio: ≥99%
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• aplicação(ões): forensics and toxicology; veterinary
• Formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]12C
• InChI: 1S/C28H37ClO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1
• chave InChI: KUVIULQEHSCUHY-XYWKZLDCSA-N
• Informações sobre genes: human ... NR3C1(2908)

Descrição

Descrição geral

Beclomethasone dipropionate belongs to the chemical class of chlorinated glucocorticoid diesters, well known for its use in the treatment of asthma due to its anti-inflammatory properties.

Aplicação

Beclomethasone dipropionate analytical standard can be used as follows:

• Development of a reversed-phase high-performance liquid chromatographic (RP-HPLC) method, combined with UV detection to determine beclomethasone dipropionate in nanocapsule suspensions
• Simultaneous determination of beclomethasone dipropionate and ketoconazole in their bulk and combined cream formulations using UV-spectrophotometry and RP-HPLC based methods
• Estimation of beclomethasone dipropionate and formoterol fumarate in their combined dosage forms by stability indicating RP-HPLC method coupled with UV detection
• Combined analysis of beclomethasone dipropionate and formoterol fumarate dihydrate using two UV-spectrometric and one RP-HPLC based methods in bulk and their pharmaceutical dosage forms
• Multi-residue analysis of 21 glucocorticoids in environmental samples by ultra-high performance liquid chromatography (UHPLC) and mass spectrometry (MS)

Outras notas

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Informações de segurança

• Pictogramas: GHS08
• Palavra indicadora: Warning
• Frases de perigo: H361fd,H373
• Declarações de precaução: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Classificações de perigo: Repr. 2 - STOT RE 2
• Órgãos-alvo: Adrenal gland,Immune system,Bone
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges