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Key Documents

PHR1180

Supelco

Imidazol

Pharmaceutical Secondary Standard; Certified Reference Material

Sinônimo(s):

1,3-Diaza-2,4-ciclopentadieno, Glioxalina

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About This Item

Fórmula empírica (Notação de Hill):
C3H4N2
Número CAS:
Peso molecular:
68.08
Beilstein:
103853
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

certified reference material
pharmaceutical secondary standard

Nível de qualidade

Agency

traceable to Ph. Eur. I0086000
traceable to USP 1336500

pressão de vapor

<1 mmHg ( 20 °C)

família API

imidazole

Certificado de análise (CofA)

current certificate can be downloaded

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

pKa (25 °C)

6.95

pb

256 °C (lit.)

pf

88-91 °C (lit.)

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-30°C

cadeia de caracteres SMILES

c1c[nH]cn1

InChI

1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)

chave InChI

RAXXELZNTBOGNW-UHFFFAOYSA-N

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Descrição geral

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

Imidazole may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography (HPLC).
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Excelente para tampões na faixa de pH de 6,2-7,8

Nota de análise

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAC4011 in the slot below. This is an example certificate only and may not be the lot that you receive.

produto relacionado

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C

Código de classe de armazenamento

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

293.0 °F - closed cup

Ponto de fulgor (°C)

145 °C - closed cup


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Imidazol ACS reagent, &#8805;99% (titration)

Sigma-Aldrich

I2399

Imidazol

Imidazol for molecular biology, &#8805;99% (titration)

Sigma-Aldrich

I5513

Imidazol

Determination of methylparaben, propylparaben, clotrimazole and its degradation products in topical cream by RP-HPLC
Solich P, et al.
Chromatographia, 56(1), S181-S184 (2002)
Chromatographic determination of clotrimazole, ketoconazole and fluconazole in pharmaceutical formulations
Abdel-Moety EM, et al.
Il Farmaco (Societa Chimica Italiana : 1989), 57(11), 931-938 (2002)
Aviva Levina et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 19(11), 3609-3619 (2013-01-31)
An anti-metastatic drug, NAMI-A ((ImH)[Ru(III) Cl4 (Im)(dmso)]; Im=imidazole, dmso=S-bound dimethylsulfoxide), and a cytotoxic drug, KP1019 ((IndH)[Ru(III) Cl4 (Ind)2 ]; Ind=indazole), are two Ru-based anticancer drugs in human clinical trials. Their reactivities under biologically relevant conditions, including aqueous buffers, protein solutions
Tomotsugu Awano et al.
Journal of bacteriology, 196(1), 140-147 (2013-10-29)
The genome of Thermococcus kodakarensis, along with those of most Thermococcus and Pyrococcus species, harbors five paralogous genes encoding putative α subunits of nucleoside diphosphate (NDP)-forming acyl coenzyme A (acyl-CoA) synthetases. The substrate specificities of the protein products for three
Eleonora Petryayeva et al.
Langmuir : the ACS journal of surfaces and colloids, 29(3), 977-987 (2013-01-10)
Methods have been developed for the solid-phase detection of nucleic acids using mixed films of quantum dots (QDs) and oligonucleotide probes in microtiter plates. Polystyrene microwells were functionalized with multidentate imidazole ligands to immobilize QDs. Oligonucleotide hybridization was transduced using

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