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Key Documents

PHR1231

Supelco

Sodium benzoate

Pharmaceutical Secondary Standard; Certified Reference Material

Sinônimo(s):

Benzoic acid sodium salt

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About This Item

Fórmula linear:
C6H5COONa
Número CAS:
Peso molecular:
144.10
Beilstein:
3572467
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

certified reference material
pharmaceutical secondary standard

Nível de qualidade

Agency

traceable to USP 1055002
traceable to USP 1613564

família API

sodium benzoate

Certificado de análise (CofA)

current certificate can be downloaded

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

pf

>300 °C (lit.)

aplicação(ões)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-30°C

cadeia de caracteres SMILES

[Na+].[O-]C(=O)c1ccccc1

InChI

1S/C7H6O2.Na/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H,8,9);/q;+1/p-1

chave InChI

WXMKPNITSTVMEF-UHFFFAOYSA-M

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Descrição geral

Sodium benzoate is a sodium salt of benzoic acid, that is freely soluble in water compared to benzoic acid. It is generally used as an antimicrobial preservative in cosmetics, food, and pharmaceuticals.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

Sodium benzoate may be used as a pharmaceutical reference standard for the determination of the analyte in raw material, food, cosmetics and pharmaceutical formulations by titrimetry and liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAC0283 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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Preços

Pictogramas

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Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Eye Irrit. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Simultaneous determination of aspartame, acesulfame-K, saccharin, citric acid and sodium benzoate in various food products using HPLC-CAD-UV/DAD
Grembecka M, et al
European Food Research and Technology, 238(3), 357-365 (2014)
High-pressure liquid chromatographic assay of dextromethorphan hydrobromide, guaifenesin, and sodium benzoate in an expectorant syrup
Chen TM, et al.
Journal of Chromatographic Science, 26(12), 636-639 (1988)
HPLC and LC-MS/MS methods for determination of sodium benzoate and potassium sorbate in food and beverages: Performances of local accredited laboratories via proficiency tests in Turkey
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Sodium Benzoate
Pharmacopeia, US
United States Pharmacopeia/National Formulary, 38(3)(1-2), 5951-5951 (2018)
Sodium Benzoate
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