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Documentos Principais

PHR1019

Supelco

Álcool benzílico

Pharmaceutical Secondary Standard; Certified Reference Material

Sinônimo(s):

Benzeno-metanol

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About This Item

Fórmula linear:
C6H5CH2OH
Número CAS:
Peso molecular:
108.14
Beilstein:
878307
Número CE:
Número MDL:
Código UNSPSC:
12352104
eCl@ss:
39023110
ID de substância PubChem:
NACRES:
NA.24

grau

certified reference material
pharmaceutical secondary standard

Nível de qualidade

Agency

traceable to Ph. Eur. Y0000167
traceable to USP 1061901

densidade de vapor

3.7 (vs air)

pressão de vapor

13.3 mmHg ( 100 °C)
3.75 mmHg ( 77 °C)

família API

benzalkonium chloride

Certificado de análise (CofA)

current certificate can be downloaded

temperatura de autoignição

817 °F

prazo de validade

~3 yr

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

índice de refração

n20/D 1.539 (lit.)

p.e.

203-205 °C (lit.)

pf

−16-−13 °C (lit.)

densidade

1.045 g/mL at 25 °C (lit.)

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-30°C

cadeia de caracteres SMILES

OCc1ccccc1

InChI

1S/C7H8O/c8-6-7-4-2-1-3-5-7/h1-5,8H,6H2

chave InChI

WVDDGKGOMKODPV-UHFFFAOYSA-N

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Descrição geral

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Benzyl alcohol is used as a preservative in pharmaceutical preparations in concentration up to 2% and as a solubilizer in concentrations of 5%. It is effective against gram-positive organisms.

Aplicação

Benzyl alcohol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and spectrophotometry.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAC1678 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

213.8 °F - DIN 51758

Ponto de fulgor (°C)

101 °C - DIN 51758


Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number

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SAFC

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Álcool benzílico

Simultaneous determination of bifonazole and benzyl alcohol in pharmaceutical formulations by reverse-phase HPLC.
Cudina OA, et al.
Chromatographia, 61(7-8), 415-418 (2005)
Full spectrum and selected spectrum based multivariate calibration methods for simultaneous determination of betamethasone dipropionate, clotrimazole and benzyl alcohol: Development, validation and application on commercial dosage form.
Darwish HW, et al.
Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 169, 50-57 (2016)
Simultaneous spectrophotometric determination of benzyl alcohol and diclofenac in pharmaceuticals using methods based on the first derivative of the optical density ratio.
Ghasemi J, et al.
Pharmaceutical Chemistry Journal, 39(12) (2005)
Simultaneous spectrophotometric determination of piroxicam and benzyl alcohol in gel forms.
Goger NG, et al.
Chem. Anal. (Warsaw), 50(6), 1059-1059 (2005)
C L Froebe et al.
Dermatologica, 181(4), 277-283 (1990-01-01)
The relationship between the in vivo irritation potential of sodium lauryl sulfate (SLS) and linear alkyl benzene sulfonate (LAS) and the ability of these two surfactants to remove lipid from the stratum corneum (SC) in vitro were investigated. Either surfactant

Protocolos

US EPA Method 8270 (Appendix IX): GC Analysis of Semivolatiles on Equity®-5 (30 m x 0.25 mm I.D., 0.50 μm)

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