383376

Potassium antimonyl tartrate trihydrate

ACS reagent, ≥99%

• Sinônimo(s): Antimony potassium tartrate trihydrate, Tartar emetic
• Fórmula empírica (Notação de Hill): C₈H₄K₂O₁₂Sb₂ · 3H₂O
• Número CAS: 28300-74-5
• Peso molecular: 667.87
• Número CE: 234-293-3
• Número MDL: MFCD00167056
• Código UNSPSC: 12352100
• ID de substância PubChem: 24863959
• NACRES: NA.21

Propriedades

• grau: ACS reagent
• Nível de qualidade: 200
• Ensaio: ≥99%; 99.0-103.0%
• forma: powder
• Impurezas: ≤0.020 meq/g Titr. acid or base
• perda: ≤2.7% loss on drying
• pf: ≥300 °C (lit.)
• solubilidade: water: soluble
• traços de cátion: As: ≤0.015%
• cadeia de caracteres SMILES: O.O.O.[K+].[K+].O=C1O[Sb-]23OC1C4O[Sb-]5(OC(C(O2)C(=O)O3)C(=O)O5)OC4=O
• InChI: 1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4
• chave InChI: WBTCZEPSIIFINA-UHFFFAOYSA-J

Descrição

Descrição geral

Potassium antimonyl tartrate trihydrate is a metalloid salt in which the antimony is in trivalent state (SbIII). Potassium antimonyl tartrate (PAT) is an antiparasitic agent predominantly used for treating infections caused by the parasite Leishmania. Its antiangiogenic and antitumor properties has been investigated in nonsmall-cell lung cancer (NSCLC) cells. Studies in Chinese hamster ovary cells show that it may prevent the repair of DNA double strand breaks (DSBs) caused by γ-irradiation.

Aplicação

Potassium antimonyl tartrate trihydrate has been used in the dose-inhibition experiments to evaluate the dose-inhibition curves of antimony-based antileishmanial compounds against Leishmania promastigotes in medium 199.

Potassium antimonyl tartrate trihydrate may be used to prepare antimony (Sb(III)) stock solution in deionized water (100mg/L). It may also be employed in the spectrophotometric determination of total phosphorus in dry sediments.

Informações de segurança

• Pictogramas: GHS06,GHS09
• Palavra indicadora: Danger
• Frases de perigo: H301,H315,H317,H332,H411
• Declarações de precaução: P261 - P273 - P280 - P301 + P310 - P302 + P352 - P304 + P340 + P312
• Classificações de perigo: Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Skin Irrit. 2 - Skin Sens. 1
• Código de classe de armazenamento: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Faceshields, Gloves