MAB2642

Anti-Fibrillin-2 Antibody, clone 48

clone 48, from mouse

• Sinônimo(s): fibrillin 2, congenital contractural arachnodactyly, Fibrillin 5
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• forma do anticorpo: purified antibody
• tipo de produto de anticorpo: primary antibodies
• clone: 48, monoclonal
• reatividade de espécies: human
• técnica(s): ELISA: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable
• Isotipo: IgG1κ
• nº de adesão NCBI: NP_001990
• nº de adesão UniProt: P35556
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... FBN2(2201)

Descrição

Descrição geral

Fibrillin-2 is a part of the Fibrillin family of glycoproteins, which are essential factors in the formation and maintenance of elastic fibers known as microfibrils within the extracellular matrix. Various researchers have suggested that Fibrillin-2 has a role in the mediation of microfibril assembly during early elastogenesis. Defects in Fibrillin-2 are causal to a rare disorder involving autosomal dominant connective tissue known as congenital contractual arachnodactyly (CCA), also known as Beals syndrome or distal arthrogryposis type 9 (DA9), and is similar to Marfan syndrome.

Especificidade

The antibody recognizes Fibrillin-2.

Imunogênio

Recombinant protein corresponding to human Fibrillin-2.

Aplicação

Anti-Fibrillin-2 Antibody, clone 48 is an antibody against Fibrillin-2 for use in IH, ELISA, IP & IC.

ELISA Analysis: A previous lot was used by an independent laboratory in ELISA (Charbonneau, 2003).

Immunofluorescence Analysis: A previous lot was used by an independent laboratory in IF (Charbonneau, 2003).

Qualidade

Evaluated by Immunohistochemistry in liver cancer and papillary serous carcinoma paraffin-embedded tissue sections.

Immunohistochemistry Analysis: 1:50 dilution of this antibody detected Fibrillin-2 in paraffin-embedded tissue sections of liver cancer and papillary serous carcinoma.

Descrição-alvo

~ 215 kDa

forma física

Format: Purified

Nota de análise

Control
Liver cancer and papillary serous carcinoma tissue

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable