1.03893

Ácido benzenossulfônico

EMPROVE^® EXPERT

• Sinônimo(s): Benzene sulphonic acid, Benzenesulphonic acid, Besylic acid, Phenylsulfonic acid, Phenylsulphonic acid
• Fórmula linear: C₆H₅SO₃H
• Número CAS: 98-11-3
• Peso molecular: 158.18
• Beilstein: 742513
• Número CE: 202-638-7
• Número MDL: MFCD00011689
• Código UNSPSC: 12352005

Propriedades

• fonte biológica: synthetic
• Nível de qualidade: 500
• linha de produto: EMPROVE^® EXPERT
• forma: crystalline
• técnica(s): API processing | cocrystal formation: suitable; API processing | salt formation: suitable
• Impurezas: endotoxins, low
• aplicação(ões): liquid formulation; parenterals; pharmaceutical
• cadeia de caracteres SMILES: OS(=O)(=O)c1ccccc1
• InChI: 1S/C6H6O3S/c7-10(8,9)6-4-2-1-3-5-6/h1-5H,(H,7,8,9)
• chave InChI: SRSXLGNVWSONIS-UHFFFAOYSA-N

Descrição

Descrição geral

For protein-based therapeutics, such as monoclonal antibodies (mAbs) or plasma derived proteins, often highly concentrated protein formulations are required to meet intended dosing regimens. However, this usually comes with elevated viscosities and presents a challenge in the manufacturing process and final formulation. Our Viscosity Reduction Excipient Platform reduces the viscosity and helps overcome challenges associated with highly concentrated protein solutions.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation.
Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Aplicação

The Viscosity Reduction Platform is based on the combination of two new excipients, one amino acid component with one anionic component, that together can better reduce protein viscosity beyond levels achieved with single excipients. Also, combining the two components enables a balance of viscosity reduction and protein stabilization. Benzenesulfonic Acid Emprove^® Expert is part of this new proprietary technology platform.

Embalagem

1038930500 / 500g / Glass bottle
1038931000 / 1kg / Glass bottle

Informações legais

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Pictogramas: GHS05,GHS07
• Palavra indicadora: Danger
• Frases de perigo: H302,H314
• Declarações de precaução: P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
• Código de classe de armazenamento: 8A - Combustible corrosive hazardous materials
• Classe de risco de água (WGK): WGK 1