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Documentos Principais

900100P

Avanti

PGE1

Avanti Research - A Croda Brand 900100P, powder

Sinônimo(s):

Prostaglandin E1

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About This Item

Fórmula empírica (Notação de Hill):
C20H34O5
Número CAS:
Peso molecular:
354.48
Número MDL:
Código UNSPSC:
12352211
NACRES:
NA.25

Formulário

powder

embalagem

pkg of 1 × 1 mg (900100P-1mg)

fabricante/nome comercial

Avanti Research - A Croda Brand 900100P

tipo de lipídio

neutral glycerides
neutral lipids

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

O=C1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C1

InChI

1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1

chave InChI

GMVPRGQOIOIIMI-DWKJAMRDSA-N

Descrição geral

Prostaglandins (PGs) belong to the group of biological compounds called eicosanoids, which are oxygen derivatives formed during arachidonic acid metabolism. PGs are localized to every tissue and body fluids in the mammals. It was first discovered in the human prostate gland, and hence got its name, prostaglandins.

Aplicação

Prostaglandin E1 (PGE1) might be used to study its ability to form silver adducts. It is also suitable for use in chemotaxis assays.

Ações bioquímicas/fisiológicas

Prostaglandins (PGs) mediate vasodilation and vasoconstriction, the E-series of prostaglandin is a highly effective vasodilator. It is known to efficiently cause erythema. PGE1 is considered as a potent pyretic factor, and acts through cerebral ventricles. It is useful to prolong cardiovascular function in newborn suffering from ductus-dependant congenital heart disease until surgery. It acts as a vasodilator. PGE1 shows Ca2+ transients in sperm as induced by progesterone.

Embalagem

5 mL Amber Glass Screw Cap Vial (900100P-1mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogramas

Skull and crossbones

Palavra indicadora

Danger

Frases de perigo

Declarações de precaução

Classificações de perigo

Acute Tox. 3 Oral

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Polina V Lishko et al.
Nature, 471(7338), 387-391 (2011-03-18)
Steroid hormone progesterone released by cumulus cells surrounding the egg is a potent stimulator of human spermatozoa. It attracts spermatozoa towards the egg and helps them penetrate the egg's protective vestments. Progesterone induces Ca(2+) influx into spermatozoa and triggers multiple
David Stanley
Annual review of entomology, 51, 25-44 (2005-12-08)
Prostaglandins and other eicosanoids are oxygenated metabolites of certain polyunsaturated fatty acids. These compounds are well known for their important actions in mammalian physiology and disease. Recent work has revealed the presence and biological actions of eicosanoids in insects and
The Prostaglandins (2013)
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Analytical and bioanalytical chemistry, 399(1), 367-376 (2010-11-12)
Spray solvent doped with silver ions increases the ease of olefin detection by desorption electrospray ionization (DESI). Characteristic silver adducts were generated in up to 50 times greater abundance when compared to conventional DESI spray solvents for the biologically significant

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