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Documentos Principais

700062P

Avanti

stigmasterol

Avanti Research - A Croda Brand

Sinônimo(s):

Stigmasterin; Phytosterol; beta-Stigmasterol; D5-Stigmasterol; 110801

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About This Item

Fórmula empírica (Notação de Hill):
C29H48O
Número CAS:
Peso molecular:
412.69
Número MDL:
Código UNSPSC:
12352211
NACRES:
NA.25

descrição

stigmasta-5,22-dien-3-ol

Ensaio

>99% (TLC)

Formulário

powder

embalagem

pkg of 1 × 5 mg (700062P-5mg)

fabricante/nome comercial

Avanti Research - A Croda Brand

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

O[C@H]1CC[C@@]2([C@@H]3[C@H]([C@H]4[C@@]([C@H](CC4)[C@H](C)\C=C\[C@H](C(C)C)CC)(CC3)C)CC=C2C1)C

InChI

1S/C29H48O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h8-10,19-21,23-27,30H,7,11-18H2,1-6H3/b9-8+/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1

chave InChI

HCXVJBMSMIARIN-PHZDYDNGSA-N

Descrição geral

Stigmasterol is a plant sterol that comprises an unsaturated bond between C22 and C23. It is found in foods like margarines and yogurts. Stigmasterol is synthesized from the mevalonate pathway and is present during development stages in plants.

Aplicação

Stigmasterol has been used as a phytosterol compound to test its anti-proliferative property in breast cancer cell culture and its effect on liver X receptor-α (LXRA) activation. It may be used as an internal standard for the quantification of yeast cell wall sterols using gas chromatography–mass spectrometry (GC-MS) analysis, and in the preparation of lipid monolayers.

Ações bioquímicas/fisiológicas

Stigmasterol possesses anti-inflammatory anti-hypercholestrolemic, antitumor and antioxidant functionality. It plays a crucial role in the activation of plasma membrane H+-ATPase and cell proliferation. Variations in stigmasterol and its precursor are noticeable at both the seed and whole plant developmental stages. Stigmasterol may be involved in gravitropism and tolerance to abiotic stress.

Embalagem

5 mL Amber Glass Screw Cap Vial (700062P-5mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

geralmente comprado junto com este produto

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Sigma-Aldrich

S9889

β-Sitosterol

cholestanol Avanti Research™ - A Croda Brand

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700064P

cholestanol

Fucosterol ≥93%

Sigma-Aldrich

F5379

Fucosterol

Brusatol ≥95% (HPLC)

Sigma-Aldrich

SML1868

Brusatol

β-Sitosterol ≥70%

Sigma-Aldrich

85451

β-Sitosterol

Katarzyna Hąc-Wydro et al.
Colloids and surfaces. B, Biointerfaces, 116, 138-146 (2014-01-28)
In this work miscibility and interactions of sterols with choline plasmalogen (PC-plasm) in Langmuir monolayers were studied. Moreover, the properties of cholesterol/phosphatidylcholine/plasmalogen mixtures of different PC-plasm concentration were investigated. The foregoing systems were treated as a model of cancer cell
Samantha A Hutchinson et al.
International journal of molecular sciences, 20(13) (2019-07-05)
Low fruit and vegetable consumption and high saturated fat consumption causes elevated circulating cholesterol and are breast cancer risk factors. During cholesterol metabolism, oxysterols form that bind and activate the liver X receptors (LXRs). Oxysterols halt breast cancer cell proliferation

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