E18859

Ethyl cyanoformate

99%

• Sinônimo(s): 2-Ethoxy-2-oxoacetonitrile, Cyanocarbonyloxyethane, Cyanoformic acid ethyl ester, Ethoxycarbonyl cyanide, Ethyl carbonocyanidate
• Fórmula linear: NCCO₂C₂H₅
• Número CAS: 623-49-4
• Peso molecular: 99.09
• Beilstein: 635955
• Número CE: 210-797-9
• Número MDL: MFCD00001836
• Código UNSPSC: 12352100
• ID de substância PubChem: 24894440
• NACRES: NA.22

Propriedades

• Nível de qualidade: 100
• Ensaio: 99%
• forma: liquid
• índice de refração: n20/D 1.381 (lit.)
• pb: 115-116 °C (lit.)
• densidade: 1.003 g/mL at 25 °C (lit.)
• cadeia de caracteres SMILES: CCOC(=O)C#N
• InChI: 1S/C4H5NO2/c1-2-7-4(6)3-5/h2H2,1H3
• chave InChI: MSMGXWFHBSCQFB-UHFFFAOYSA-N

Descrição

Aplicação

Ethyl cyanoformate can be used as a cyanide source for the cyanation of:

• Activated olefins in the presence of a titanium catalyst.
• Carbonyl compounds catalyzed by 4-dimethylaminopyridine (DMAP) to yield corresponding cyanohydrin carbonates under metal-free and solvent-free conditions.
• Aldehydes and 2,2,2-trifluoroacetophenone catalyzed by N-heterocyclic carbene (NHC) to yield corresponding cyanohydrins ethyl carbonates.

Ethyl cyanoformate is a general cyanating agent. It can be used in the nucleophilic addition of cyanide to carbonyl compounds, oxidative cyanation of tertiary amines and in the synthesis of β-cyano-substituted acrylates from alkynes.

Informações de segurança

• Pictogramas: GHS02,GHS05
• Palavra indicadora: Danger
• Frases de perigo: H226,H314
• Declarações de precaução: P210 - P280 - P303 + P361 + P353 - P305 + P351 + P338 + P310
• Classificações de perigo: Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B
• Código de classe de armazenamento: 3 - Flammable liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 75.2 °F - closed cup
• Ponto de fulgor (°C): 24 °C - closed cup
• Equipamento de proteção individual: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter