799718

AlPhos

• Sinônimo(s): Di-1-adamantyl(4″-butyl-2″,3″,5″,6″-tetrafluoro-2′,4′,6′-triisopropyl-2-methoxy-meta-terphenyl)phosphine
• Fórmula empírica (Notação de Hill): C₅₂H₆₇F₄OP
• Número CAS: 1805783-60-1
• Peso molecular: 815.06
• Número MDL: MFCD00626457
• Código UNSPSC: 12161600
• ID de substância PubChem: 329768101
• NACRES: NA.22

Propriedades

• Ensaio: ≥95%
• Nível de qualidade: 100
• Formulário: powder
• adequação da reação: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand; reaction type: Cross Couplings
• pf: 218-223 °C
• grupo funcional: phosphine
• temperatura de armazenamento: −20°C
• InChI: 1S/C52H67F4OP/c1-9-10-12-38-46(53)48(55)45(49(56)47(38)54)44-40(29(4)5)21-39(28(2)3)43(42(44)30(6)7)37-13-11-14-41(57-8)50(37)58(51-22-31-15-32(23-51)17-33(16-31)24-51)52-25-34-18-35(26-52)20-36(19-34)27-52/h11,13-14,21,28-36H,9-10,12,15-20,22-27H2,1-8H3/t31-,32+,33?,34-,35+,36?,51+,52?,58?
• chave InChI: ALWIRDZSIXWCBO-VABCSHEKSA-N

Descrição

Aplicação

AlPhos is a biaryl monophosphine ligand that can be used:

• In the Pd-catalyzed Buchwald-Hartwig cross-coupling reactions.
• To synthesize highly regioselective aryl fluorides by Pd-catalyzed fluorination of a variety of activated aryl and heteroaryl triflates and bromides.
• To prepare aryl thioethers by C–S cross-coupling of thiols with aromatic electrophile in the presence of palladium catalyst.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3