795569

Garg 4,5-indolyne precursor

95%

• Sinônimo(s): 4-(Trimethylsilyl)-1H-indol-5-yl trifluoromethanesulfonate
• Fórmula empírica (Notação de Hill): C₁₂H₁₄F₃NO₃SSi
• Número CAS: 1259448-37-7
• Peso molecular: 337.39
• Número MDL: MFCD25976536
• Código UNSPSC: 12352100
• ID de substância PubChem: 329768491
• NACRES: NA.22

Propriedades

• Nível de qualidade: 100
• Ensaio: 95%
• Formulário: solid
• pf: 43-48 °C
• grupo funcional: fluoro; triflate
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: O=S(OC1=C([Si](C)(C)C)C2=C(NC=C2)C=C1)(C(F)(F)F)=O
• InChI: 1S/C12H14F3NO3SSi/c1-21(2,3)11-8-6-7-16-9(8)4-5-10(11)19-20(17,18)12(13,14)15/h4-7,16H,1-3H3
• chave InChI: LLCJFYYASDIOJN-UHFFFAOYSA-N

Descrição

Descrição geral

Garg 4,5-indolyne precursor is an indolyne precursor developed by Professor Neil Garg and coworkers. It is widely used for the synthesis of various N-heterocyclic based compounds. It is also useful for the preparation of substituted indoles (Diels–Alder and azide cycloaddition products).

Aplicação

Indolyne precursor can be activated under mild fluoride conditions, which are highly reactive with dienes and other dipolariphiles (e.g. azides) to provide cycloaddition products containing an indole motif.

Outras notas

Indolyne Experimental and Computational Studies: Synthetic Applications and Origins of Selectivities of Nucleophilic Additions

Regioselective reactions of 3; 4-pyridynes enabled by the aryne distortion model

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H315,H319,H335
• Declarações de precaução: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classificações de perigo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable