544639

Methanesulfonylacetone

97%

• Sinônimo(s): 1-(Methylsulfonyl)-2-propanone, NSC 35395
• Fórmula linear: CH₃C(O)CH₂SO₂CH₃
• Número CAS: 5000-46-4
• Peso molecular: 136.17
• Número CE: 225-665-6
• Número MDL: MFCD00014745
• Código UNSPSC: 12352100
• ID de substância PubChem: 24878779
• NACRES: NA.22

Propriedades

• Nível de qualidade: 100
• Ensaio: 97%
• Formulário: powder or crystals
• pf: 48-52 °C (lit.)
• grupo funcional: ketone; sulfone
• cadeia de caracteres SMILES: CC(=O)CS(C)(=O)=O
• InChI: 1S/C4H8O3S/c1-4(5)3-8(2,6)7/h3H2,1-2H3
• chave InChI: NWEYGXQKFVGUFR-UHFFFAOYSA-N

Descrição

Descrição geral

Methanesulfonylacetone is a sulfonyl group-containing active methylene compound. It can react with Baylis–Hillman acetates in dimethylformamide/potassium carbonate system to form ortho-hydroxyacetophenone derivatives.

Aplicação

Methanesulfonylacetone may be used in the preparation of 6-bromo-3-methanesulfonyl-2-methyl-quinolin-4-ol.

Reactant for:

• Stereoselective preparation of chiral cyclic ketones
• Preparation of poly-substituted pyridines
• Multicomponent cyclocondensation with aldehydes and aminoazoles
• Gold-catalyzed Friedlander cyclocondensation reaction
• Radical homoallylation reactions

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)