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512443

Sigma-Aldrich

3-Chloro-L-tyrosine

97%

Sinônimo(s):

(2S)-2-Amino-3-(3-chloro-4-hydroxyphenyl)propanoic acid, Monochlorotyrosine

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About This Item

Fórmula linear:
4-(HO)C6H3(Cl)CH2CH(NH2)CO2H
Número CAS:
7423-93-0
Peso molecular:
215.63
Número CE:
231-050-3
Número MDL:
MFCD00045865
Código UNSPSC:
12352209
eCl@ss:
32160406
ID de substância PubChem:
24873634
NACRES:
NA.22

Ensaio

97%

atividade óptica

[α]24/D −2°, c = 1 in 1 M HCl

adequação da reação

reaction type: solution phase peptide synthesis

pf

249 °C (lit.)

aplicação(ões)

peptide synthesis

cadeia de caracteres SMILES

N[C@@H](Cc1ccc(O)c(Cl)c1)C(O)=O

InChI

1S/C9H10ClNO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1

chave InChI

ACWBBAGYTKWBCD-ZETCQYMHSA-N

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
MKCP5653
MKCJ5561
09001EA
05730TS

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L-Tyrosine reagent grade, ≥98% (HPLC)

Sigma-Aldrich

T3754

L-Tyrosine

Protease Type XIV, ≥3.5 units/mg solid, powder

Sigma-Aldrich

P5147

Protease

Ácido trifluoracético ReagentPlus®, 99%

Sigma-Aldrich

T6508

Ácido trifluoracético

Jihan Talib et al.
Free radical biology & medicine, 53(1), 20-29 (2012-05-23)
Smokers have an elevated risk of atherosclerosis but the origin of this elevated risk is incompletely defined, though increasing evidence supports a role for the oxidant-generating enzyme myeloperoxidase (MPO). In previous studies we have demonstrated that smokers have elevated levels
J J Provencio et al.
Neurocritical care, 12(2), 244-251 (2009-12-08)
Cerebral vasospasm is a significant cause of morbidity in patients after aneurysmal subarachnoid hemorrhage (aSAH). There are few effective treatments. The search for new treatments has focused predominantly on dilating cerebral blood vessels. Growing evidence supports a role for inflammation
Laetitia Mouls et al.
Proteomics, 9(6), 1617-1631 (2009-03-03)
Protein oxidation is thought to contribute to a number of inflammatory diseases, hence the development of sensitive and specific analytical techniques to detect oxidative PTMs (oxPTMs) in biological samples is highly desirable. Precursor ion scanning for fragment ions of oxidized
Eline Thomson et al.
Free radical biology & medicine, 49(9), 1354-1360 (2010-07-22)
We aimed to determine whether myeloperoxidase (MPO) is the main peroxidase present in the airways of children with cystic fibrosis (CF) and to assess which oxidants it produces and whether they are associated with clinical features of CF. Children with
Joseph I Kang et al.
Chemical research in toxicology, 21(5), 1028-1038 (2008-05-03)
While the last 30 years chronicles an extensive effort to understand the damage to DNA caused by reactive oxygen species (ROS), little research has examined the chemical damage to the histone proteins found in chromatin. Hypochlorous acid (HOCl), the primary
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