415057

Magnesium stearate

technical grade

• Sinônimo(s): Stearic acid magnesium salt
• Fórmula linear: [CH₃(CH₂)₁₆CO₂]₂Mg
• Número CAS: 557-04-0
• Peso molecular: 591.24
• Beilstein: 3919702
• Número CE: 209-150-3
• Número MDL: MFCD00036391
• Código UNSPSC: 12352100
• ID de substância PubChem: 24865972
• NACRES: NA.22

Propriedades

• grau: technical grade
• forma: powder
• composição: palmitate salt, 25% ; stearate salt, 65%
• pf: 200 °C (lit.)
• cadeia de caracteres SMILES: CCCCCCCCCCCCCCCCCC(=O)O[Mg]OC(=O)CCCCCCCCCCCCCCCCC
• InChI: 1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
• chave InChI: HQKMJHAJHXVSDF-UHFFFAOYSA-L

Descrição

Descrição geral

Magnesium stearate (Mg-St) is the magnesium salt of stearic acid. Its anhydrate, dihydrate and trihydrate forms have been prepared. The tabletting of the blends of magnesium stearate and lactose granules has been described. The influence of mixing time on hardness, disintegration time and ejection force on the compressed tablets was examined. Mg-St is widely used lubricant in pharmaceutical industry. It also plays a role in delaying the process of dissolution. Its detection in tablets by laser-induced breakdown spectroscopy has been proposed.

Magnesium stearate, the salt of stearic acid, is widely employed as an inactive component in making pharmaceutical tablets.

Aplicação

Magnesium stearate may be used as excipient in the formulations of diclofenac sodium tablets. It may be used for the preparation of tramadol HCl matrix tablets.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves