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327190

Sigma-Aldrich

Isobutyl nitrite

95%

Sinônimo(s):

2-Methylpropyl nitrite

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About This Item

Fórmula linear:
(CH3)2CHCH2ONO
Número CAS:
542-56-3
Peso molecular:
103.12
Número CE:
208-819-7
Número MDL:
MFCD00002056
Código UNSPSC:
12352100
ID de substância PubChem:
24859648
NACRES:
NA.22

Nível de qualidade

100

Ensaio

95%

forma

liquid

índice de refração

n20/D 1.373 (lit.)

pb

66-67 °C (lit.)

densidade

0.87 g/mL at 25 °C (lit.)

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CC(C)CON=O

InChI

1S/C4H9NO2/c1-4(2)3-7-5-6/h4H,3H2,1-2H3

chave InChI

APNSGVMLAYLYCT-UHFFFAOYSA-N

Categorias relacionadas

Descrição geral

Isobutyl nitrite was extensively used as room odorizers. It is a popular recreational drug.

Aplicação

Isobutyl nitrite was used to study inhalant-induced immunotoxicity.

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Flam. Liq. 2 - Muta. 2

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

-5.8 °F - closed cup

Ponto de fulgor (°C)

-21 °C - closed cup

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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L S Soderberg et al.
Experimental hematology, 24(7), 848-853 (1996-06-01)
Isobutyl nitrite is representative of a group of inhalants abused primarily by male homosexuals; abuse of this drug may be a risk factor for AIDS or Kaposi's sarcoma. Using a 14-day exposure regimen, we previously reported that inhaled isobutyl nitrite
L S F Soderberg et al.
Toxicology letters, 152(1), 47-56 (2004-08-06)
Epidemiological studies have identified abuse of nitrite inhalants as an independent co-factor in HIV infection and in Kaposi's sarcoma (KS) in AIDS patients. In the present study we investigated the ability of macrophages from mice exposed to isobutyl nitrite to
S M Bradberry et al.
Journal of toxicology. Clinical toxicology, 32(2), 179-184 (1994-01-01)
Isobutyl nitrite is a popular recreational drug among both homosexuals and heterosexuals as it is alleged to enhance sexual pleasure and prolong orgasm. In contrast to the ingestion of this volatile nitrite, inhalation is associated only rarely with serious sequelae
Lee S F Soderberg et al.
Toxicology letters, 132(1), 37-45 (2002-06-27)
Nitrite inhalant abuse has been correlated with HIV and Kaposi's sarcoma. Mouse models of inhalant exposure show immunosuppression and loss of immune cells. In the present study, isobutyl nitrite caused a dose-dependent loss of viability of a macrophage cell line.
[Methemoglobinemia due to ingestion of isobutyl nitrite ('poppers')].
W G Zijlstra
Nederlands tijdschrift voor geneeskunde, 147(23), 1144-1144 (2003-06-26)
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