Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos Principais

Visualizar Toda a Documentação

142859

Sigma-Aldrich

Difluoroacetic acid

98%

Sinônimo(s):

1,1-Difluoroacetic acid, 2,2-Difluoroacetic acid

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(1)

About This Item

Fórmula linear:
F2CHCO2H
Número CAS:
381-73-7
Peso molecular:
96.03
Beilstein:
1098588
Número CE:
206-839-0
Número MDL:
MFCD00004220
Código UNSPSC:
12352106
ID de substância PubChem:
24848539
NACRES:
NA.22

Nível de qualidade

200

Ensaio

98%

forma

liquid

índice de refração

n20/D 1.344 (lit.)

pb

132-134 °C (lit.)

pf

−1 °C (lit.)

densidade

1.526 g/mL at 25 °C (lit.)

grupo funcional

carboxylic acid
fluoro

cadeia de caracteres SMILES

OC(=O)C(F)F

InChI

1S/C2H2F2O2/c3-1(4)2(5)6/h1H,(H,5,6)

chave InChI

PBWZKZYHONABLN-UHFFFAOYSA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Descrição geral

Difluoroaceticacid is a monocarboxylic acid and an organofluorine compound. Difluoroaceticacid is easy-to-handle reagent, useful for obtaining difluoromethyl substituents. Difluoroacetic acid can be used asdifluoromethylating reagent for the direct C−H difluoromethylation ofheteroaromatic compounds.

Aplicação

Used in the preparation of 2-difluoromethylbenzimidazoles, -oxazoles and -thiazoles from ortho-substituted anilines mediated by triphenylphoshine.

Pictogramas

CorrosionExclamation mark
GHS05,GHS07

Palavra indicadora

Danger

Frases de perigo

H314,H332,H412

Classificações de perigo

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

Código de classe de armazenamento

8A - Combustible corrosive hazardous materials

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

172.4 °F - closed cup

Ponto de fulgor (°C)

78 °C - closed cup

Equipamento de proteção individual

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
BCCG6767
BCCG3677
BCCD8331
BCCD7060
BCCD0681

Não está vendo a versão correta?

Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

Pesquise por COA

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 6

1 of 6

Ethyl bromodifluoroacetate 98%

Sigma-Aldrich

295795

Ethyl bromodifluoroacetate

Sodium chlorodifluoroacetate 96%

Sigma-Aldrich

374067

Sodium chlorodifluoroacetate

Ethyl fluoroacetate 98%

Sigma-Aldrich

163813

Ethyl fluoroacetate

Dichloroacetic acid ReagentPlus®, ≥99%

Sigma-Aldrich

D54702

Dichloroacetic acid

3,3,3-Trifluoro-2,2-dimethylpropionic acid 97%

Sigma-Aldrich

684694

3,3,3-Trifluoro-2,2-dimethylpropionic acid

3-Fluorotoluene 99%

Sigma-Aldrich

162329

3-Fluorotoluene

N Illy et al.
Comptes rendus des seances de la Societe de biologie et de ses filiales, 175(2), 242-246 (1981-01-01)
Our experiments were carried out in normal and streptozotocin-diabetic rats. The effects of sodium difluoroacetate (DFA) at the dose of 40 mg/kg daily were studied on the blood and retinal lactate levels; these effects were compared to those of an
Brian M Wagner et al.
Journal of chromatography. A, 1489, 75-85 (2017-02-19)
To facilitate mass transport and column efficiency, solutes must have free access to particle pores to facilitate interactions with the stationary phase. To ensure this feature, particles should be used for HPLC separations which have pores sufficiently large to accommodate
Tetrahedron Letters, 48, 3251-3251 (2007)
J N Commandeur et al.
Biochemical pharmacology, 37(23), 4495-4504 (1988-12-01)
The biotransformation and the hepato- and nephrotoxicity of the mercapturic acids (N-acetyl-1-cysteine S-conjugates) of three structurally related 2,2-difluoroethylenes were investigated in vivo in the rat. All mercapturic acids appeared to cause nephrotoxicity, without any measureable effect on the liver. The
Ute Dorgerloh et al.
Molecules (Basel, Switzerland), 24(6) (2019-03-17)
The concentrations of difluoroacetic acid (DFA) and trifluoroacetic acid (TFA) in rainwater and surface water from Berlin, Germany resembled those reported for similar urban areas, and the TFA/DFA ratio in rainwater of 10:1 was in accordance with the literature. In
Exibir todos os documentos relacionados

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica