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Sigma-Aldrich

3,3-Diphenylpropylamine

97%

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About This Item

Fórmula linear:
(C6H5)2CHCH2CH2NH2
Número CAS:
5586-73-2
Peso molecular:
211.30
Número CE:
226-984-3
Número MDL:
MFCD00008202
Código UNSPSC:
12352100
ID de substância PubChem:
24848275
NACRES:
NA.22

Ensaio

97%

índice de refração

n20/D 1.583 (lit.)

pf

29-31 °C (lit.)

cadeia de caracteres SMILES

NCCC(c1ccccc1)c2ccccc2

InChI

1S/C15H17N/c16-12-11-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10,15H,11-12,16H2

chave InChI

KISZTEOELCMZPY-UHFFFAOYSA-N

Aplicação

3,3-Diphenylpropylamine was used as internal standard for simultaneous determination of D- and L-modafinil in human plasma using stereospecific high-performance liquid chromatographic method. It was used as starting reagent in the synthesis of 3,3-diphenylpropylisocyanate.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315,H319,H335

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

235.4 °F - closed cup

Ponto de fulgor (°C)

113 °C - closed cup

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

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A L Mueller et al.
Annals of the New York Academy of Sciences, 890, 450-457 (2000-02-11)
NPS 1506 is a moderate affinity, uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. NPS 1506 is neuroprotective in rodent models of ischemic stroke, hemorrhagic stroke, and head trauma, with a 2-hr window of opportunity. Neuroprotectant doses of NPS 1506 ranged from approximately
B Elsenhans et al.
Biochimica et biophysica acta, 813(1), 25-32 (1985-02-28)
Cationic, lipid-soluble organic compounds may interfere with cation-mediated membrane transport processes. Thus, small intestinal absorption may be influenced by lipophilic organic cations. Therefore a series of arylalkylamines was studied in the concentration range from 0.5 to 20 mmol/l for their
S H Gorman
Journal of chromatography. B, Biomedical sciences and applications, 730(1), 1-7 (1999-08-07)
Modafinil, DL-2-[(diphenylmethyl)sulfinyl]acetamide (Provigil), which is chiral at its sulfur atom, is a novel wake-promoting agent currently being developed as the racemate in the United States by Cephalon, Inc. In order to characterize the pharmacokinetic properties of each enantiomer, a stereospecific
T F Holzman et al.
Biochemistry, 20(19), 5524-5528 (1981-09-15)
We have found a new class of inhibitors of the bacterial bioluminescence reaction, the N,N-diphenylalkylamines and acids. We have studied the action of one of these compounds 2,2-diphenylpropylamine. The amine was competitive with the long-chain aliphatic aldehyde substrate (Ki congruent
Shiv K Sharma et al.
Journal of medicinal chemistry, 53(14), 5197-5212 (2010-06-24)
The recently discovered enzyme lysine-specific demethylase 1 (LSD1) plays an important role in the epigenetic control of gene expression, and aberrant gene silencing secondary to LSD1 overexpression is thought to contribute to the development of cancer. We recently reported a

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