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135828

Sigma-Aldrich

Benzamide

99%

Sinônimo(s):

Benzoic acid amide

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About This Item

Fórmula linear:
C6H5CONH2
Número CAS:
55-21-0
Peso molecular:
121.14
Beilstein:
385876
Número CE:
200-227-7
Número MDL:
MFCD00007968
Código UNSPSC:
12352100
ID de substância PubChem:
24848219
NACRES:
NA.22

Nível de qualidade

100

Ensaio

99%

pf

125-128 °C (lit.)

solubilidade

ethanol: soluble 50 mg/mL, clear to very slightly hazy, colorless to light yellow

grupo funcional

amide
phenyl

cadeia de caracteres SMILES

NC(=O)c1ccccc1

InChI

1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9)

chave InChI

KXDAEFPNCMNJSK-UHFFFAOYSA-N

Informações sobre genes

human ... PARP1(142)

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Descrição geral

Benzamide on radioiodination by different labeling procedures results in large-scale production of radioiodinated benzamides having potential therapeutic application for patients with metastatic malignant melanoma.

Benzamide is used as a building block in organic synthesis for the preparation of various biologically active compounds.

Aplicação

Benzamide was used to study the mechanism of photocatalytic decomposition of aqueous solution of acetic acid, acetamide and acetonitrile in the presence of semiconductors. It was used to develop a robust screening method to study biotransformations using (+)-γ-lactamase enzyme.

Ações bioquímicas/fisiológicas

Inhibits poly(ADP-ribose) polymerase (PARP).

Pictogramas

Health hazardExclamation mark
GHS08,GHS07

Palavra indicadora

Warning

Frases de perigo

H302,H341

Classificações de perigo

Acute Tox. 4 Oral - Muta. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

356.0 °F - closed cup

Ponto de fulgor (°C)

180 °C - closed cup

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
STBK5339
STBK3229
STBK1028
STBJ8084
STBJ8054

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Sigma-Aldrich

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Sigma-Aldrich

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Walter Mier et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(1), 9-14 (2013-11-28)
The performance of cytotoxic drugs is defined by their selectivity of uptake and action in tumor tissue. Recent clinical responses achieved by treating metastatic malignant melanoma with therapeutic modalities based on gene expression profiling showed that malignant melanoma is amenable
Photocatalytic Decompositions of Carboxylic Acid Derivatives by Semiconductors.
Park KH and Kim JH.
Bull. Korean Chem. Soc., 12(4), 439-439 (1991)
Willian G Birolli et al.
Pesticide biochemistry and physiology, 156, 129-137 (2019-04-28)
Chiral pesticides have been used in agriculture, including (±)-lambda-cyhalothrin ((±)-LC), which is a pyrethroid insecticide widely employed on crops for protection against different types of insects. However, enantioselectivity is poorly studied in biodegradation processes. Therefore, the (±)-LC enantioselective biodegradation by
Jamin D Steffen et al.
Journal of medicinal chemistry, 54(15), 5403-5413 (2011-06-23)
The metabolism of poly(ADP-ribose) (PAR) in response to DNA strand breaks, which involves the concerted activities of poly(ADP-ribose) polymerases (PARPs) and poly(ADP-ribose) glycohydrolase (PARG), modulates cell recovery or cell death depending upon the level of DNA damage. While PARP inhibitors
Anne Marie Hickey et al.
Biotechnology journal, 4(4), 510-516 (2009-03-18)
A (+)-gamma-lactamase was precipitated, cross-linked and the resulting solid crushed prior to immobilisation within a capillary column microreactor. The microreactor was subsequently used to study enzyme stability, activity, kinetics and substrate specificity. The thermophilic (+)-gamma-lactamase retained 100% of its initial
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