399337

Benzamide

purified by sublimation, ≥99.5%

• Sinônimo(s): Benzoic acid amide
• Fórmula linear: C₆H₅CONH₂
• Número CAS: 55-21-0
• Peso molecular: 121.14
• Beilstein: 385876
• Número CE: 200-227-7
• Número MDL: MFCD00007968
• Código UNSPSC: 12352100
• ID de substância PubChem: 24864807
• NACRES: NA.22

Propriedades

• Ensaio: ≥99.5%
• Formulário: powder
• purificado por: sublimation
• pf: 125-128 °C (lit.)
• solubilidade: ethanol: soluble 50 mg/mL, clear to slightly hazy, colorless to light yellow
• grupo funcional: amide; phenyl
• cadeia de caracteres SMILES: NC(=O)c1ccccc1
• InChI: 1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9)
• chave InChI: KXDAEFPNCMNJSK-UHFFFAOYSA-N
• Informações sobre genes: human ... PARP1(142)

Descrição

Descrição geral

Benzamide (Benzoic acid amide, BA) is an amide of benzoic acid. BA on crystallization in benzene (solvent) affords crystals suitable for X-ray analysis. Crystal structure studies suggest that its crystals are monoclinic having space group P2₁/c. Kinetics and mechanism of its reaction with hydrogen peroxide have been proposed.

Aplicação

Benzamide was used to study the mechanism of photocatalytic decomposition of aqueous solution of acetic acid, acetamide and acetonitrile in the presence of semiconductors. Benzamide was used to develop a robust screening method to study biotransformations using (+)-γ-lactamase enzyme.

Ações bioquímicas/fisiológicas

Inhibits poly(ADP-ribose) polymerase (PARP).

Informações de segurança

• Pictogramas: GHS08,GHS07
• Palavra indicadora: Warning
• Frases de perigo: H302,H341
• Declarações de precaução: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Classificações de perigo: Acute Tox. 4 Oral - Muta. 2
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 356.0 °F - closed cup
• Ponto de fulgor (°C): 180 °C - closed cup
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves