SAE0091
Lysostaphin from Staphylococcus staphylolyticus
free of DNA contaminants, suitable for Microbiome research, lyophilized powder, ≥500 units/mg protein
Recommended Products
biological source
microbial (Staphylococcus staphylotyticus)
form
lyophilized powder
specific activity
≥500 units/mg protein
mol wt
27 kDa
feature
DNA free
shipped in
wet ice
storage temp.
−20°C
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This Item | SRE0053 | L2898 | L7386 |
|---|---|---|---|
| biological source microbial (Staphylococcus staphylotyticus) | biological source - | biological source - | biological source microbial (Staphylococcus staphylotyticus) |
| form lyophilized powder | form lyophilized powder | form powder | form lyophilized powder |
| mol wt 27 kDa | mol wt 26,926 Da | mol wt 25 kDa | mol wt 25 kDa |
| shipped in wet ice | shipped in wet ice | shipped in - | shipped in wet ice |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| specific activity ≥500 units/mg protein | specific activity ≥500 units/mg protein | specific activity >500 units/mg protein | specific activity ≥500 units/mg protein |
Application
Lysostaphin is a zinc metalloenzyme isolated from a bacterial culture of Staphylococcus staphylolyticus. It has specific lytic action against other Staphylococcus species, including S. aureus.1,2 Lysostaphin has
hexosaminidase, amidase, and endopeptidase activities. It cleaves polyglycine crosslinks in the cellular wall which leads to cell lysis of Staphylococcus species, but not of other bacterial genera. [Pharmaceuticals 2010, 3(4), 1139-1161]
Lysostaphin is a single polypeptide chain of 246 amino acids, a molecular mass of 26,926 Da, isoelectric point of 9.5, (5) and an activity pH optimum of 7.5.(6)
Biochem/physiol Actions
pH Optimum for activity: ~7.5
Unit Definition
Physical form
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Resp. Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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