Zoe Loomis et al.
PloS one, 12(2), e0171219-e0171219 (2017-02-06)
It is now well established that both inherited and acquired forms of hemolytic disease can promote pulmonary vascular disease consequent of free hemoglobin (Hb) induced NO scavenging, elevations in reactive oxygen species and lipid peroxidation. It has recently been reported...
Chunxia Xiao et al.
PloS one, 7(1), e30343-e30343 (2012-01-25)
The C57BLKS/J db/db (db/db) mouse is a widely used type 2 diabetic animal model, and this model develops early inner retinal neuronal dysfunction beginning at 24 weeks. The neural mechanisms that mediate early stage retinal dysfunction in this model are...
Lipotoxic brain microvascular injury is mediated by activating transcription factor 3-dependent inflammatory and oxidative stress pathways
Aung HH, et al.
Journal of Lipid Research, 57(6), 955-968 (2016)
The structural biochemistry of the superoxide dismutases
Perry JJP, et al.
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics, 1804(2), 245-262 (2010)
Walid Nachar et al.
PloS one, 14(8), e0220707-e0220707 (2019-08-09)
Left ventricular diastolic dysfunction (LVDD) is present in more than 50% of patients suffering from heart failure. LVDD animal models are limited and its underlying mechanisms remain largely unknown. Aortic valve stenosis (AVS) may cause LVDD, and we recently reported...