574594

Superoxide Dismutase, Bovine Erythrocytes

• Synonym(s): Superoxide Dismutase, Bovine Erythrocytes, Cu/Zn SOD
• CAS Number: 9054-89-1
• Enzyme Commission number: 1.15.1.1 (BRENDA, IUBMB)
• MDL number: MFCD00132404
• UNSPSC Code: 12352202
• NACRES: NA.54

Properties

• biological source: bovine erythrocytes
• Quality Level: 100
• form: lyophilized solid
• specific activity: ≥3000 units/mg dry wt.
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated
• pI: 4.95
• solubility: 50 mM potassium phosphate, 100 μM EDTA, pH 7.8: 5 mg/mL, clear, pale blue
• foreign activity: Carbonic anhydrase ≤30 U/mg (dry weight)
• shipped in: ambient
• storage temp.: −20°C

Description

General description

Native superoxide dismutase from bovine erythrocytes. Essential component of biological defense against toxic effects of oxygen. Catalyzes the dismutation of superoxide radicals to oxygen and H₂O₂.

Note: 1 KU = 1000 units.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Unit Definition

One unit is defined as the amount of enzyme that will cause a 50% inhibition in the rate of reduction of cytochrome c at 25°C, pH 7.8.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C).

Other Notes

Tilly, J.L. and Tilly, K.I. 1995. Endocrinology136, 242.
Sharonov, B.P. and Churilova, I.V. 1992. Biochem. Biophys. Res. Commun.189, 1129.
Britton, L., et al. 1978. J. Bacteriol. 134, 229.
Keele, B.B., et al. 1971. J. Biol. Chem.246, 2875.
McCord, J.M. and Fridovich, I. 1969. J. Biol. Chem.244, 6049.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS08
• signalword: Danger
• hcodes: H334
• pcodes: P261 - P284 - P501
• Hazard Classifications: Resp. Sens. 1
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable