P5607

L-Proline

from non-animal source, meets EP, USP testing specifications, suitable for cell culture

• Synonym(s): (S)-Pyrrolidine-2-carboxylic acid
• Empirical Formula (Hill Notation): C₅H₉NO₂
• CAS Number: 147-85-3
• Molecular Weight: 115.13
• Beilstein: 80810
• EC Number: 205-702-2
• MDL number: MFCD00064318
• eCl@ss: 32160406
• PubChem Substance ID: 24898677

Properties

• biological source: non-animal source
• Quality Level: 200
• Agency: meets EP testing specifications; meets USP testing specifications
• assay: 98.5-101.0% dry basis
• form: powder
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• color: white
• mp: 228 °C (dec.) (lit.)
• solubility: H₂O: 50 mg/mL
• application(s): pharmaceutical (small molecule)
• SMILES string: OC(=O)[C@@H]1CCCN1
• InChI: 1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1
• InChI key: ONIBWKKTOPOVIA-BYPYZUCNSA-N

Description

Application

L-proline has been used as a component of high-glucose-Dulbecco′s modified Eagle′s medium (HG-DMEM) for chondrocyte differentiation and for the culture of chondrocyte-like cells. It has also been used as a component of yeast nitrogen base for yeast cultures.

Packaging

25, 100 g in poly bottle

1 kg in poly bottle

25 kg in poly drum

Biochem/physiol Actions

Proline is a cyclic, non-essential, hydrophobic amino acid. It is a proteinogenic amino acid which is crucial for primary metabolism. In peptide chains, proline residues confer structural constraints and enhance the susceptibility of proximal peptide bonds to protease activity.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves