Skip to Content
MilliporeSigma
All Photos(4)

Key Documents

I7403

Sigma-Aldrich

L-Isoleucine

98.5-101.0%, suitable for cell culture, BioXtra, non-animal source

Synonym(s):

(2S,3S)-2-Amino-3-methylpentanoic acid

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
C2H5CH(CH3)CH(NH2)CO2H
CAS Number:
Molecular Weight:
131.17
Beilstein/REAXYS Number:
1721792
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

product name

L-Isoleucine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%

biological source

non-animal source

Quality Level

agency

USP/NF
meets EP testing specifications
meets JP testing specifications
meets USP testing specifications

product line

BioXtra

assay

98.5-101.0%

form

powder

quality

meets EP, JP, USP testing specifications

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

mp

288 °C (dec.) (lit.)

solubility

1 M HCl: 50 mg/mL

application(s)

peptide synthesis
pharmaceutical (small molecule)

SMILES string

CC[C@H](C)[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1

InChI key

AGPKZVBTJJNPAG-WHFBIAKZSA-N

Looking for similar products? Visit Product Comparison Guide

Application

L-Isoleucine has been used as a supplement of maintenance media consisting of DMEM/F-12 for the culture of primary hepatocytes. It has also been used as a supplement for serial culture of adult murine keratinocytes.

Biochem/physiol Actions

L-Isoleucine is an essential amino acid that is synthesized from threonine. It is a branched-chain hydrophobic amino acid. L-isoleucine is an isomer of L-leucine.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Conversion of ammonia or urea into essential amino acids,L-leucine,L-valine, andL-isoleucine using artificial cells containing an immobilized multienzyme system and dextran-NAD+
Kang Fu Gu
Applied Biochemistry and Biotechnology, 26 (1990)
Biochemistry (5th Edition) null
Inhibitory effect of aroma on the bitterness of branched-chain amino acid solutions.
Mukai J
Chemical & Pharmaceutical Bulletin, 55(11), 1581-1584 (2007)
Serial Cultivation of Primary Adult Murine Keratinocytes
Richard P. Redvers and Pritinder Kaur
Methods in Molecular Biology (2005)
Recapitulation of metabolic defects in a model of propionic acidemia using patient-derived primary hepatocytes.
Chapman KA
Molecular Genetics and Metabolism, 117(3), 355-362 (2016)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service