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P0380

Sigma-Aldrich

L-Proline

ReagentPlus®, ≥99% (HPLC)

Synonym(s):
(S)-Pyrrolidine-2-carboxylic acid
Empirical Formula (Hill Notation):
C5H9NO2
CAS Number:
Molecular Weight:
115.13
Beilstein:
80810
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

Quality Level

product line

ReagentPlus®

assay

≥99% (HPLC)

form

powder

application(s)

detection: suitable

impurities

L-Hydroxyproline, free

color

white

mp

228 °C (dec.) (lit.)

SMILES string

OC(=O)[C@@H]1CCCN1

InChI

1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1

InChI key

ONIBWKKTOPOVIA-BYPYZUCNSA-N

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Application

L-Proline has been used:
  • As a supplement during the preparation of chondrogenic medium and synthetic dextrose minimal medium (SD).
  • As a standard during the identification of metabolites in serum samples.
  • In a study to prepare L-proline-L-phenylalanine (L-Pro-L-Phe) mixture in aqueous acetonitrile.

Packaging

100 g in poly bottle
10 mg in glass bottle
1 kg in poly bottle
5 kg in poly drum

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Mieczysław Sajewicz et al.
Journal of chromatographic science, 53(1), 31-37 (2014-03-05)
We employ the achiral liquid chromatography with diode array, evaporative light scattering and mass spectrometric detection (HPLC-DAD, HPLC-ELSD and LC-MS) to assess structural instability (understood as spontaneous oscillatory chiral conversion and spontaneous oscillatory condensation) of the two pairs of amino...
Metabolomic insights into system-wide coordination of vertebrate metamorphosis.
Ichu TA, et al.
BMC Developmental Biology, 14(1), 1-1 (2014)
Natasja Leth Joergensen et al.
BioResearch open access, 4(1), 109-114 (2015-08-27)
Cartilage regeneration is a fast growing field that combines biotechnology and molecular techniques in creating new tissue mimicking the native microenvironment. Human embryonic stem cells (hESCs) are a highly potent cell source for cartilage regeneration owing to their infinite proliferation...
Quantification of extracellular ammonium concentrations and transporter activity in yeast using AmTrac fluorescent sensors.
Ast C, et al.
Bio-protocol, 5, e1372-e1372 (2015)
Proline: a multifunctional amino acid
La' szlo' Szabados and Arnould Savoure
Trends in Plant Science, 1-9 (2009)

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