Skip to Content
MilliporeSigma
All Photos(4)

Key Documents

S4500

Sigma-Aldrich

L-Serine

≥99% (HPLC), ReagentPlus®

Synonym(s):

(S)-2-Amino-3-hydroxypropionic acid

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
HOCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
105.09
Beilstein/REAXYS Number:
1721404
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

product name

L-Serine, ReagentPlus®, ≥99% (HPLC)

Quality Level

product line

ReagentPlus®

assay

≥99% (HPLC)

form

powder

color

white to off-white

mp

222 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL, clear, colorless

application(s)

detection

storage temp.

room temp

SMILES string

N[C@@H](CO)C(O)=O

InChI

1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

InChI key

MTCFGRXMJLQNBG-REOHCLBHSA-N

Looking for similar products? Visit Product Comparison Guide

Application

L-Serine has been used in the preparation of Tris-BSAN buffer for homogenization. It has also been used for quantitative analysis of excretion of polypeptides in normal urine.

Biochem/physiol Actions

L-Serine is a non-essential amino acid that acts as a precursor for nucleotide synthesis. It has roles in the development and function of the central nervous system. L-Serine also has a role in cellular proliferation.
Precursor of glycine by serine hydroxymethyltransferase.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Taiga Okumura et al.
Scientific reports, 8(1), 9707-9707 (2018-06-28)
Radiocesium-bearing microparticles (CsPs) substantially made of silicate glass are a novel form of radiocesium emitted from the broken containment vessel of Fukushima Dai-ichi nuclear power plant. CsPs have a potential risk of internal radiation exposure caused by inhalation. Radiation-contaminated waste
L-Serine in disease and development
Tom J. de Koning
Biochemistry, 371 (2003)
Taiga Okumura et al.
Scientific reports, 9(1), 3520-3520 (2019-03-07)
Radiocaesium-bearing microparticles (CsMPs) composed of silicate glass were released by the Fukushima Daiichi Nuclear Power Plant accident in March 2011. Since CsMPs contain a high concentration of radiocaesium, their dynamics and fate in the environment are urgent issues to be
Abel Lajtha, Simo S. Oja, Pirjo Saransaari, Arne Schousboe
Handbook of Neurochemistry and Molecular Neurobiology: Amino Acids and Peptides in the Nervous System, 4 (2007)
Analysis of GSH and GSSG after derivatization with N-ethylmaleimide
Nature Protocols, 8(9) (2003)

Articles

Neoplastic cells are highly dependent on the de novo synthesis of nucleotides to maintain sufficient pools to support DNA replication and the production of RNA.

Chromatograms

application for HPLCapplication for HPLC

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service