L3916
L-Lactic Dehydrogenase from bovine heart
1000 units/mL
Synonym(s):
Lactate, (S)-Lactate: NAD+ oxidoreductase, L-LDH, LAD, LD
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General description
LDH (lactic dehydrogenase) is a glycolytic enzyme. It is found in skeletal muscle, heart, liver, kidneys, brain, lungs and red blood cells. It comprises of five isoenzyme forms. LDH possess a tetrameric structure.
Application
L-Lactic Dehydrogenase from bovine heart has been used:
- as a reference standard to measure the LDH (lactic dehydrogenase)
- to quench protein-bound NADH in cells
- to measure the lactate released by the cells in suspension
For use in enzymatic determination of lactate or pyruvate.
Biochem/physiol Actions
LDH (lactic dehydrogenase) helps in the reversible conversion of lactate to pyruvate.
Also catalyzes the oxidation of other L-2-hydroxymonocarboxylic acids.
Unit Definition
One unit will reduce 1.0 μmole of pyruvate to L-lactate per min at pH 7.5 at 37 °C.
Physical form
Suspension in 2.2 M ammonium sulfate
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
ppe
Eyeshields, Gloves, type N95 (US)
Certificates of Analysis (COA)
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Articles
Instructions for working with enzymes supplied as ammonium sulfate suspensions
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