F8775

Sigma-Aldrich

Formaldehyde solution

for molecular biology, 36.5-38% in H2O

Synonym(s):
Formalin
Linear Formula:
HCHO
CAS Number:
Molecular Weight:
30.03
Beilstein/REAXYS Number:
1209228
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.31

Quality Level

grade

for molecular biology

vapor density

1.03 (vs air)

vapor pressure

52 mmHg ( 37 °C)

form

liquid

autoignition temp.

572 °F

contains

10-15% methanol

concentration

36.5-38% in H2O

density

1.09 g/mL at 25 °C (lit.)

suitability

suitable for (use in Formaldehyde-Agarose Gel Electrophoresis of RNA)

storage temp.

15-25°C

SMILES string

[H]C([H])=O

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Formaldehyde (formalin) is produced by oxidation of methanol. It is made of 37% formaldehyde and impurities such as methanol, small amounts of formic acid, aldehydes and ketones. It is used as a denaturant in formaldehyde-agarose gel electrophoresis of RNA. A gel concentration of 2.2M formaldehyde is typically used. The formaldehyde concentration as supplied is approximately 13.3M.

Application

Formaldehyde solution has been used for fixing of cells and tissue sections. It has been used in the formaldehyde agarose gel electrophoresis. Formaldehyde is used as a denaturant in formaldehyde-agarose gel electrophoresis of RNA.

Packaging

25, 500 mL in poly bottle

Analysis Note

Tested for use in formaldehyde-agarose gel electrophoresis of RNA.

Signal Word

Danger

hazcat

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 1 - STOT SE 3

Target Organs

Respiratory system

storage_class_code

3 - Flammable liquids

WGK Germany

WGK 3

Flash Point(F)

133.0 °F - closed cup

Flash Point(C)

56.11 °C - closed cup

Certificate of Analysis

Certificate of Origin

Lun Zhao et al.
Nature communications, 10(1), 3640-3640 (2019-08-15)
Insight into high-resolution three-dimensional genome organization and its effect on transcription remains largely elusive in plants. Here, using a long-read ChIA-PET approach, we map H3K4me3- and RNA polymerase II (RNAPII)-associated promoter-promoter interactions and H3K9me2-marked heterochromatin interactions at nucleotide/gene resolution in rice....
RNA-dependent RNA Polymerase Assay for Hepatitis E Virus.
Nair VP et al.
Bio-protocol null
Farrell RE
RNA Methodologies: A Laboratory Guide for Isolation and Characterization (2010)
Claire E J Moore et al.
Cellular signalling, 28(4), 284-293 (2016-01-23)
Eukaryotic elongation factor 2 kinase (eEF2K) inhibits the elongation stage of protein synthesis by phosphorylating its only known substrate, eEF2. eEF2K is tightly regulated by nutrient-sensitive signalling pathways. For example, it is inhibited by signalling through mammalian target of rapamycin...
Burry RW
Immunocytochemistry: A Practical Guide for Biomedical Research (2009)
Protocols
The Sigma Imprint Chromatin Immunoprecipitation Kit uses a plate based system to allow rapid ChIP assays in a high throughput format
Read More

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service