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C2211

Sigma-Aldrich

Z-Leu-Leu-Leu-al

≥90% (HPLC)

Synonym(s):
MG-132
Empirical Formula (Hill Notation):
C26H41N3O5
CAS Number:
Molecular Weight:
475.62
MDL number:
PubChem Substance ID:
NACRES:
NA.32

Quality Level

Assay

≥90% (HPLC)

form

powder

color

white

solubility

DMSO: soluble

storage temp.

−20°C

SMILES string

[H]C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1

InChI

1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22-,23-/m0/s1

InChI key

TZYWCYJVHRLUCT-VABKMULXSA-N

Gene Information

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Z-Leu-Leu-Leu-al ≥90% (HPLC)

Sigma-Aldrich

C2211

Z-Leu-Leu-Leu-al

Z-Asp(OtBu)-OH ≥98.0% (TLC)

Sigma-Aldrich

02378

Z-Asp(OtBu)-OH

Z-Dehydro-Ala-OMe ≥98.0% (TLC)

Sigma-Aldrich

96077

Z-Dehydro-Ala-OMe

assay

≥90% (HPLC)

assay

≥98%

assay

≥98.0% (TLC)

assay

≥98.0% (TLC)

form

powder

form

powder

form

powder or crystals

form

crystals

color

white

color

white

color

white

color

-

solubility

DMSO: soluble

solubility

THF: 25 mg/mL, clear, colorless

solubility

-

solubility

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

storage temp.

-

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

Amino Acid Sequence

Z-Leu-Leu-Leu-al

Application

Z-Leu-Leu-Leu-al or MG132 has been used as a proteasome inhibitor. It has also been used to test the ubiquitylation and sumoylation pathways in urchin embryos.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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