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L0879

Sigma-Aldrich

Leu-Leu-Leu

≥90% (elemental analysis), suitable for mass spectrometry (MS)

Synonym(s):

Trileucine

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About This Item

Empirical Formula (Hill Notation):
C18H35N3O4
CAS Number:
10329-75-6
Molecular Weight:
357.49
MDL number:
MFCD00038309
UNSPSC Code:
12352202
PubChem Substance ID:
24896267
NACRES:
NA.26

product name

Leu-Leu-Leu, ≥90% (elemental analysis)

assay

≥90% (elemental analysis)

form

powder

technique(s)

electron microscopy: suitable
mass spectrometry (MS): suitable

color

white

storage temp.

−20°C

SMILES string

CC(C)CC(N)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(O)=O

InChI

1S/C18H35N3O4/c1-10(2)7-13(19)16(22)20-14(8-11(3)4)17(23)21-15(18(24)25)9-12(5)6/h10-15H,7-9,19H2,1-6H3,(H,20,22)(H,21,23)(H,24,25)

InChI key

DNDWZFHLZVYOGF-UHFFFAOYSA-N

Related Categories

Amino Acid Sequence

Leu-Leu-Leu

Application

Trileucine (Leu-Leu-Leu), an endosome escape moiety, may be used for pH-dependent endosomal membrane disruption to release agents such as antisense oligonucleotides (AONs) inside cells. Trileucine is used to evaluate the absorption characteristics of reversed phase liquid chromatography (HPLC) media.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Journal of chromatography. A, 1216(18), 3992-4004 (2009-03-31)
The single-component equilibrium adsorption of the tripeptide Leucyl-Leucyl-Leucine (LLL) on a high-efficiency Jupiter Proteo column (C(12)) was investigated experimentally and modeled theoretically. The experimental equilibrium isotherms of LLL for adsorption on a C(12) packing material from an aqueous solution of
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