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B2629

Sigma-Aldrich

Betaine

≥98% (perchloric acid titration)

Synonym(s):
(Carboxymethyl)trimethylammonium inner salt, Oxyneurine, Trimethylglycine
Linear Formula:
(CH3)3N+CH2COO-
CAS Number:
Molecular Weight:
117.15
Beilstein:
3537113
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

biological source

sugar beets

Quality Level

assay

≥98% (perchloric acid titration)

form

powder or crystals

mp

310 °C (dec.)

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

C[N+](C)(C)CC([O-])=O

InChI

1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3

InChI key

KWIUHFFTVRNATP-UHFFFAOYSA-N

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General description

Betaine is a quaternary ammonium zwitterion, extensively present in animals, plants and microorganisms. It also forms a good dietary source as it is found in wheat, spinach, shellfish and sugar beets. Betaine is a methyl derivative of the amino acid glycine. It is known by different names such as trimethylglycine, glycine betaine, lycine and oxyneurine.

Application

Betaine has been used to study the effects of antioxidants on regrowth from cryopreservation.

Packaging

50, 100 g in poly bottle
1 kg in poly bottle

Biochem/physiol Actions

Apart from betaine taking part in transmethylation, it acts as an organic osmolyte in protecting cells under stress. This is being significantly observed in plants and microorganisms. Betaine is also known to increase the levels of S-adenosylmethionine and thus this might reduce the effects of hepatic steatosis.
End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.

Other Notes

Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

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