49419

Sigma-Aldrich

L-Glutamine

BioUltra, ≥99.5% (NT)

Synonym(s):
Levoglutamide, L-Glutamic acid 5-amide, (S)-2,5-Diamino-5-oxopentanoic acid
Linear Formula:
H2NCOCH2CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
146.14
Beilstein/REAXYS Number:
1723797
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

product line

BioUltra

Quality Level

assay

≥99.5% (NT)

form

powder

optical activity

[α]20/D +33.0±1°, c = 5% in 5 M HCl

application(s)

cell culture | mammalian: suitable

impurities

insoluble matter, passes filter test
≤0.5% foreign amino acids

ign. residue (900 °C)

≤0.1% (as SO4)

loss

≤0.1% loss on drying, 110 °C

color

white

pH

5.0-6.0 (25 °C, 0.1 M in H2O)

mp

185 °C (dec.) (lit.)

solubility

H2O: 0.1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤200 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

0.1 M in H2O

UV absorption

λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01

SMILES string

N[C@@H](CCC(N)=O)C(O)=O

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1

InChI key

ZDXPYRJPNDTMRX-VKHMYHEASA-N

Gene Information

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Related Categories

Application

L-Glutamine has been used in culture medium for hypothalamic neurons, spacer in isotachophoresis of serum proteins, growth requirement of various microorganisms.

Biochem/physiol Actions

L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

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CRC Handbook of Microbiology, 4, 1-1 (1974)
Techniques for culture of hypothalamic neurons.
C Loudes et al.
Methods in enzymology, 103, 313-334 (1983-01-01)
T. Yagi et al. et al.
Electrophoresis ?83, 503-503 (1984)
Rebekah M Samsonraj et al.
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