05129

L-Alanine

BioUltra, ≥99.5% (NT)

• Synonym(s): (S)-2-Aminopropionic acid, L-α-Aminopropionic acid
• Empirical Formula (Hill Notation): C₃H₇NO₂
• CAS Number: 56-41-7
• Molecular Weight: 89.09
• Beilstein: 1720248
• EC Number: 200-273-8
• MDL number: MFCD00064410
• eCl@ss: 32160406
• PubChem Substance ID: 329747639
• NACRES: NA.26

Properties

• product line: BioUltra
• Quality Level: 200
• Assay: ≥99.5% (NT)
• form: powder or crystals
• optical activity: [α]20/D +14.0±1.0°, c = 5% in 5 M HCl
• impurities: insoluble matter, passes filter test; ≤0.3% foreign amino acids
• ign. residue: ≤0.05%
• loss: ≤0.05% loss on drying, 20 °C (HV)
• color: colorless to white
• pH: 5.5-7.0 (25 °C, 1 M in H₂O)
• mp: 314.5 °C
• solubility: H₂O: 1 M at 20 °C, clear, colorless
• anion traces: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• cation traces: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; NH₄⁺: ≤100 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 1 M in H₂O
• UV absorption: λ: 260 nm A_max: ≤0.03; λ: 280 nm A_max: ≤0.02
• application(s): detection
• SMILES string: C[C@H](N)C(O)=O
• InChI: 1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1
• InChI key: QNAYBMKLOCPYGJ-REOHCLBHSA-N
• Gene Information: human ... CA1(759) , CA2(760)

Description

Biochem/physiol Actions

Alanine is a nonessential amino acid that plays a key role in the glucose-alanine cycle between muscle tissue and the liver. In amino acid-degrading tissues such as muscle, amino groups are pooled as glutamate by transamination reactions. The amino group of glutamate is transferred to pyruvate via alanine aminotransferase, forming alanine and α-ketoglutarate. The alanine is passed into the blood and transported to the liver. This reaction is reversed in the liver where pyruvate can be used in gluconeogenesis to form glucose, which may return to other tissues through the circulatory system. Increased alanine levels correlate with higher blood pressure, energy intake, cholesterol levels, and body mass index.

Other Notes

Postulated salting-in effect on proteins; Growth requirement of a variety of microorganisms.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves