MilliporeSigma
All Photos(1)

43816

Sigma-Aldrich

DL-Dithiothreitol solution

BioUltra, for molecular biology, ~1 M in H2O

Synonym(s):
(±)-threo-1,4-Dimercapto-2,3-butanediol solution, DTT
Empirical Formula (Hill Notation):
C4H10O2S2
CAS Number:
Molecular Weight:
154.25
Beilstein:
1719757
MDL number:
PubChem Substance ID:
NACRES:
NA.25

grade

for molecular biology

Quality Level

product line

BioUltra

form

liquid

concentration

~1 M in H2O

impurities

DNases, none detected
RNases, none detected
phosphatases, none detected
proteases, none detected

pH

2.7-5.0

density

1.04 g/mL at 20 °C

absorption

cut-off at 330 nm

suitability

in accordance for filter test

storage temp.

2-8°C

SMILES string

O[C@H](CS)[C@H](O)CS

InChI

1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1

InChI key

VHJLVAABSRFDPM-QWWZWVQMSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

DL-dithiothreitol solution has been used:
  • in the treatment of intestinal explants
[54]
  • in homogenate preparation of gill cells for enzymatic assays
  • [04]
  • in western blotting
  • [58]
  • in transglutaminase activity
  • [59]

    Biochem/physiol Actions

    DL-dithiothreitol (DTT) is used in a chemical debonding technique, that helps to remove bacteria from biofilms.[61] It can change the structural stability of the GABA(B) (gamma-aminobutyric acid) receptor by disabling the disulfide bonds between four cysteine residues positioned in the GABA(B1(a)) receptor structure.[53]

    Pictograms

    Corrosion

    Signal Word

    Danger

    Hazard Statements

    Hazard Classifications

    Eye Dam. 1 - Skin Irrit. 2

    Storage Class Code

    10 - Combustible liquids

    WGK

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable

    Personal Protective Equipment

    dust mask type N95 (US), Eyeshields, Gloves

    Certificate of Analysis

    Enter Lot Number to search for Certificate of Analysis (COA).

    Certificate of Origin

    Enter Lot Number to search for Certificate of Origin (COO).

    More Documents

    SDS

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service