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T4885

Sigma-Aldrich

Trichloroacetic acid

≥99.0% (titration)

Synonym(s):
TCA
Linear Formula:
Cl3CCOOH
CAS Number:
Molecular Weight:
163.39
Beilstein:
970119
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

vapor density

<1 (vs air)

Quality Level

vapor pressure

1 mmHg ( 51 °C)

Assay

≥99.0% (titration)

refractive index

n20/D 1.62 (lit.)

bp

196 °C (lit.)

mp

54-58 °C (lit.)

solubility

H2O: 1 g/10 mL

density

1.62 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

OC(=O)C(Cl)(Cl)Cl

InChI

1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key

YNJBWRMUSHSURL-UHFFFAOYSA-N

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1 of 4

This Item
T639991230T8657
Trichloroacetic acid &#8805;99.0% (titration)

Sigma-Aldrich

T4885

Trichloroacetic acid

Trichloroacetic acid ACS reagent, &#8805;99.0%

Sigma-Aldrich

T6399

Trichloroacetic acid

Trichloroacetic acid ACS reagent, for the determination of Fe in blood according to Heilmeyer, &#8805;99.5%

Sigma-Aldrich

91230

Trichloroacetic acid

Trichloroacetic acid suitable for electrophoresis, suitable for fixing solution (for IEF and PAGE gels), &#8805;99%

Sigma-Aldrich

T8657

Trichloroacetic acid

vapor density

<1 (vs air)

vapor density

<1 (vs air)

vapor density

<1 (vs air)

vapor density

<1 (vs air)

vapor pressure

1 mmHg ( 51 °C)

vapor pressure

1 mmHg ( 51 °C)

vapor pressure

1 mmHg ( 51 °C)

vapor pressure

1 mmHg ( 51 °C)

assay

≥99.0% (titration)

assay

≥99.0%

assay

≥99.5% (T)

assay

≥99%

refractive index

n20/D 1.62 (lit.)

refractive index

n20/D 1.62 (lit.)

refractive index

n20/D 1.62 (lit.)

refractive index

n20/D 1.62 (lit.)

bp

196 °C (lit.)

bp

196 °C (lit.)

bp

196 °C (lit.)

bp

196 °C (lit.)

mp

54-58 °C (lit.)

mp

54-58 °C (lit.)

mp

54-58 °C (lit.)

mp

54-58 °C (lit.)

Application

Trichloroacetic acid (TCA) can be used as a catalyst to synthesize:
  • β-enaminones via condensation reaction of 1,3-dicarbonyl compounds and amines.
  • 6-amino-3-methyl-1,4-diphenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile derivatives via four-component condensation reaction of ethyl acetoacetate, phenylhydrazine, malononitrile, and aromatic aldehydes.
  • Tetrahydrobenzo[a]xanthen-11-ones by three-component reaction of aldehydes, 2-naphthol and dimedone.

Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

Pictograms

CorrosionEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A

Storage Class Code

8B - Non-combustible, corrosive hazardous materials

WGK

WGK 2

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

> 113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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