MilliporeSigma
All Photos(1)

91230

Sigma-Aldrich

Trichloroacetic acid

ACS reagent, for the determination of Fe in blood according to Heilmeyer, ≥99.5%

Synonym(s):
TCA
Linear Formula:
Cl3CCOOH
CAS Number:
Molecular Weight:
163.39
Beilstein:
970119
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

grade

ACS reagent

vapor density

<1 (vs air)

vapor pressure

1 mmHg ( 51 °C)

assay

≥99.5% (T)
≥99.5%

form

flakes

quality

for the determination of Fe in blood according to Heilmeyer

ign. residue

≤0.03% (as SO4)

refractive index

n20/D 1.62 (lit.)

bp

196 °C (lit.)

mp

54-58 °C (lit.)

solubility

water: soluble 81.7 g/L at 20 °C

density

1.62 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤10 mg/kg
nitrate (NO3-): ≤20 mg/kg
phosphate (PO43-): ≤5 mg/kg
sulfate (SO42-): ≤200 mg/kg

cation traces

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

SMILES string

OC(=O)C(Cl)(Cl)Cl

InChI

1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key

YNJBWRMUSHSURL-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Trichloroacetic acid (TCA) is a chlorinated acetic acid. It is one of the major metabolites of trichloroethylene (TCE).

Application

Trichloroacetic acid may be used in the following studies:
  • Estimation of phosphorus in various biological samples (serum, urine and stool ash solutions).
  • Elimination of acid-soluble and lipid phosphorous during the determination of deoxyribonucleic acid, ribonucleic acid and phosphoproteins in animal tissues.
  • Preparation of 2-methyl-4-nitroanilinium trichloroacetate trichloroacetic acid (2M4NATCA) crystals.

10% Trichloroacetic acid may be employed for the preparation of radioactive proteins.
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

Other Notes

Protein denaturant

Pictograms

CorrosionEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A

Storage Class Code

8B - Non-combustible, corrosive hazardous materials

WGK

WGK 2

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

> 113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service