MilliporeSigma
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T5500

Sigma-Aldrich

2-Thiobarbituric acid

≥98%

Synonym(s):
4,6-Dihydroxy-2-mercaptopyrimidine, 4,6-Dihydroxypyrimidine-2-thiol, TBA
Empirical Formula (Hill Notation):
C4H4N2O2S
CAS Number:
Molecular Weight:
144.15
Beilstein:
120663
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

assay

≥98%

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

mp

245 °C (dec.) (lit.)

SMILES string

O=C1CC(=O)NC(=S)N1

InChI

1S/C4H4N2O2S/c7-2-1-3(8)6-4(9)5-2/h1H2,(H2,5,6,7,8,9)

InChI key

RVBUGGBMJDPOST-UHFFFAOYSA-N

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General description

2-Thiobarbituric acid is a molecule made up of heteroatoms: nitrogen, sulphur and oxygen.[45]

Application

2-Thiobarbituric acid has been used to measure malondialdehyde (MDA) in lipid peroxidation assay.[46][47][18]

Packaging

25, 100, 250, 500 g in poly bottle

Biochem/physiol Actions

2-Thiobarbituric acid (TBA) is useful to quantitate lipopolysaccharides, carrageenan, and sialic acids. It is also used to detect lipid hydroperoxides and lipid oxidation.[44] It has applications in the field of medicine and biochemistry. TBA may possess the ability to prevent metal corrosion.[45]

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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